左西孟坦治疗慢性收缩性心衰疗效观察  

Efficacy of levosimendan in the treatment of chronic systolic heart failure

作　　者：徐向文 Xu Xiangwen(The People's Hospital of Linyi City,Shandong Linyi 276000)

机构地区：[1]临沂市人民医院,山东临沂276000

出　　处：《中国社区医师》2021年第11期55-56,共2页Chinese Community Doctors

摘　　要：目的:分析左西孟坦治疗慢性收缩性心衰的临床疗效。方法:2019年1月-2020年1月收治慢性收缩性心衰患者84例,随机分为两组,各42例。对照组采取硝普钠治疗;观察组采取左西孟坦治疗。比较两组治疗效果。结果:观察组治疗总有效率明显高于对照组,差异有统计学意义(P<0.05);观察组治疗后血氧分压(PaO2)、氧合指数(PaO2/FiO2)及左心射血分数(LVEF)指标水平均高于对照组,氧化碳分压(PaCO2)水平低于对照组,差异有统计学意义(P<0.05);与对照组相比较,观察组患者的不良反应发生率更低,差异有统计学意义(P<0.05)。结论:左西孟坦治疗慢性收缩性心衰的效果明显,能够促进患者血气指标水平及心功能指标水平的改善。Objective:To explore the efficacy of levosimendan in the treatment of chronic systolic heart failure.Methods:From January 2019 to January 2020,84 patients with chronic systolic heart failure were selected and randomly divided into two groups with 42 cases in each group.The control group was treated with sodium nitroprusside.The observation group was treated with levosimendan.We compared the treatment effect of the two groups.Results:The total effective rate of the observation group was significantly higher than that of the control group,the difference was statistically significant(P<0.05).In the observation group,after treatment,PaO2,PaO2/FiO2 and LVEF were higher than those in the control group,PaCO2 was lower than that in the control group,the difference was statistically significant(P<0.05);Compared with the control group,the incidence of adverse reactions in observation group was lower,and the difference was statistically significant(P<0.05).Conclusion:The efficacy of levosimendan in the treatment of chronic systolic heart failure is better,it can promote the improvement of blood gas index and cardiac function index.

关 键 词：慢性收缩性心衰 左西孟坦 临床疗效 心功能状态 

分 类 号：R541.6[医药卫生—心血管疾病]