胺碘酮联合美托洛尔治疗快速心律失常的疗效及安全性分析  

Efficacy and safety analysis of amiodarone combined with metoprolol in the treatment of tachyarrhythmia

作　　者：卢建军 Lu Jianjun(Department of Internal Medicine,The Hospital of Traditional Chinese Medicine of Xiaochang County,Xiaogan City,Hubei Province,Hubei Xiaogan 432900)

机构地区：[1]湖北省孝感市孝昌县中医医院内科,湖北孝感432900

出　　处：《中国社区医师》2021年第12期43-44,共2页Chinese Community Doctors

摘　　要：目的:探究胺碘酮联合美托洛尔治疗快速心律失常的临床疗效。方法:2017年8月-2019年12月收治快速心律失常患者109例,随机分为两组。对照组仅采用胺碘酮治疗;试验组则采用胺碘酮联合美托洛尔治疗。比较两组治疗效果。结果:试验组治疗后舒张压(DBP)、收缩压(SBP)、心率(HR)水平均低于对照组,差异有统计学意义(P<0.05);试验组治疗后二尖瓣口血流频率(E/A)、心输出血量(CO)、左室射血分数(EF)水平均高于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:快速心律失常采用胺碘酮联合美托洛尔治疗的临床疗效显著,有利于改善患者心功能,且用药安全性高。Objective:To explore the clinical effect of amiodarone combined with metoprolol in the treatment of tachyarrhythmia.Methods:From August 2017 to December 2019,109 patients with tachyarrhythmia who were selected and randomly divided into two groups.The control group was treated with amiodarone only.The experimental group was treated with amiodarone combined with metoprolol.The therapeutic effects between the two groups was compared.Results:After treatment,diastolic blood pressure(DBP),systolic blood pressure(SBP)and heart rate(HR)in experimental group were lower than the control group,with the differences were statistically significant(P<0.05).After treatment,the mitral orifice blood flow rate frequency(E/A),cardiac output(CO)and left ventricular ejection fraction(EF)levels in experimental group were higher than the control group,with the differences were statistically significant(P<0.05).The incidence of adverse reactions between the two groups was compared,with the difference was not statistically significant(P>0.05).Conclusion:Amiodarone combined with metoprolol has significant clinical efficacy in the treatment of tachyarrhythmia,which is beneficial to improve cardiac function and has high safety.

关 键 词：快速心律失常 单独用药 联合治疗 美托洛尔 胺碘酮 安全性 

分 类 号：R541.7[医药卫生—心血管疾病]