经皮冠状动脉介入治疗慢性完全闭塞病变对患者心脏功能的影响  

Effects of percutaneous coronary intervention on cardiac function in patients with chronic total occlusion lesions

作　　者：畅晓燕[1] 赵江峰[2] CHANG Xiaoyan;ZHAO Jiangfeng(Department of Cardiology,Second Affiliated Hospital of He’nan University of Science and Technology,Luoyang,He'nan,471000,China;Department of Cardiology,First Affiliated Hospital of He’nan University of Science and Technology)

机构地区：[1]河南科技大学第二附属医院心内科,河南洛阳471000 [2]河南科技大学第一附属医院心内科

出　　处：《临床心血管病杂志》2021年第3期220-223,共4页Journal of Clinical Cardiology

摘　　要：目的:观察行经皮冠状动脉介入(PCI)治疗成功开通慢性完全闭塞(CTO)病变是否能改善患者的心脏功能。方法:回顾性纳入我院2016年1月—2018年1月行冠状动脉造影证实单支CTO病变且接受PCI治疗的患者132例,根据CTO是否开通,将所纳入患者分为开通组(70例)和未开通组(62例)。收集患者的基本临床资料,记录并比较随访期间院外主要不良心脑血管事件(MACCE)、心功能NYHA分级、左室射血分数(LVEF)、左心室舒张末期内径(LVEDD)等。结果:随访1年,未开通组和开通组在心功能NYHA分级、LVEF[(53.56±8.93)%∶(62.83±8.94)%]、LVEDD[(51.69±5.10)mm∶(48.60±5.51)mm]、全因死亡率(11.3%∶1.4%)、再次血运重建率(19.4%∶7.1%)和总MACCE发生率(40.3%∶11.4%)方面差异均具有统计学意义(均P<0.05)。结论:CTO开通能够改善患者左室功能、优化心室肌重构,降低MACCE的发生率。Objective:To observe whether the successful opening of CTO lesions by percutaneous coronary intervention(PCI)can improve the cardiac function.Methods:A total of 132 patients with single CTO lesion confirmed by coronary angiography and received PCI treatment from January 2016 to January 2018 were retrospectively included and divided into CTO-enabled group(n=70)and CTO-disabled group(n=62).The basic clinical data were collected and the follow-up results such as major adverse cardiovascular and cerebrovascular events(MACCE),heart function(NYHA grade),left ventricular ejection fraction(LVEF),and left ventricular end diastolic diameter(LVEDD)were recorded.Results:After a one-year follow-up,there were significant differences in NYHA grade,LVEF([53.56±8.93]%vs[62.83±8.94]%),LVEDD([51.69±5.10]mm vs[48.60±5.51]mm),all-cause mortality(11.3%vs 1.4%),revascularization rate(19.4%vs 7.1%),and total MACCE incidence(all P<0.05).Conclusion:CTO opening can improve left ventricular function,optimize ventricular remodeling,and reduce the incidence of MACCE.

关 键 词：慢性完全闭塞病变 经皮冠状动脉介入术 心脏功能 

分 类 号：R543.3[医药卫生—心血管疾病]