球囊辅助栓塞技术治疗未破裂颅内动脉瘤的有效性及安全性分析  

Analysis of the Effect of Balloon-assisted Embolization in the Treatment of Unruptured Intracranial Aneurysms

作　　者：于海东[1] 马存凯[1] 杨海明[1] 孙世蒙 郭应兴[1] YU Hai-dong;MA Cun-kai;YANG Hai-ming;SUN Shi-meng;GUO Ying-xing(Department of Interventional Diagnosis and Treatment,Affiliated Hospital of Qinghai University,Xining,Qinghai,810000,China)

机构地区：[1]青海大学附属医院介入诊疗科,青海西宁810000

出　　处：《现代生物医学进展》2021年第5期962-966,共5页Progress in Modern Biomedicine

基　　金：青海省卫计委医药卫生指导性项目(2017-wjzdx-62)。

摘　　要：目的:探究球囊辅助栓塞技术治疗未破裂颅内动脉瘤的有效性和安全性。方法:选择2014年1月~2019年1月在本院介入诊疗科接受介入治疗的540例患者作为研究对象。根据治疗方案分为两组,球囊辅助栓塞组有340例,单纯栓塞组有200例。回顾性分析研究对象的一般资料、临床资料、手术并发症等情况。结果:球囊辅助栓塞组和单纯栓塞组在性别组成、年龄、颅内动脉瘤性质、位置、Hunt-Hess分级等方面,差异不具有统计学意义(P>0.05);在术后即刻及术后6个月血管造影结果显示,前者栓塞程度明显优于后者,两组差异具有统计学意义(P<0.05);前者改良Rankin量表评分明显优于后者,两组差异具有统计学意义(P=0.005);前者预后良好率明显高于后者,两组差异具有统计学意义(P<0.001);手术过程中,球囊辅助栓塞组发生2例破裂出血、2例脑血管痉挛、1例弹簧圈移位,单纯栓塞组发生2例破裂出血、1例栓塞、2例脑血管痉挛、3例弹簧圈移位。前者并发症发生率明显低于后者,两者差异具有统计学意义(P<0.001)。结论:在治疗未破裂颅内动脉瘤方面,球囊辅助栓塞技术的有效性、安全性明显优于单纯栓塞介入治疗,值得临床推广。Objective:To explore the effectiveness and safety of balloon-assisted embolization in the treatment of unruptured intracranial aneurysms.Methods:From January 2014 to January 2019,540 patients who received interventional therapy in the interventional department of our hospital were selected as the research subjects.According to the treatment plan,it was divided into two groups,namely,balloon-assisted embolization group(340 cases)and simple embolization group(200 cases).We retrospectively analyzed the general information,clinical data,and surgical complications of all patients.Results:The balloon-assisted embolization group and the simple embolization group were not statistically significant in terms of gender composition,age,nature,location of intracranial aneurysm,Hunt-Hess classification(P>0.05).The results of angiography immediately after operation and 6 months after operation showed that the embolization degree of the balloon-assisted embolization group was significantly better than that of the simple embolization group,the difference was statistically significant(P<0.05).The modified Rankin of the balloon-assisted embolization group The scale score was significantly better than the simple embolization group,the difference was statistically significant(P=0.005).The prognosis rate of the balloon-assisted embolization group was significantly higher than that of the simple embolization group,the difference was statistically significant(P<0.001).During the operation In the balloon-assisted embolization group,2 cases of rupture and bleeding,2 cases of cerebral vasospasm,and 1 case of coil displacement occurred.In the simple embolization group,2 cases of rupture and bleeding,1 case of embolization,2 cases of cerebral vasospasm,and 3 cases of coil displacement.The incidence of complications in the balloon-assisted embolization group was significantly lower than that in the simple embolization group,and the difference was statistically significant(P<0.001).Conclusion:In the treatment of unruptured intracranial aneurys

关 键 词：介入治疗 颅内动脉瘤 球囊辅助栓塞 脑血管痉挛 

分 类 号：R651.1[医药卫生—外科学] R739.41[医药卫生—临床医学]