新型冠状病毒肺炎患者血液中红细胞体积参数的变化  

The Changes of RBC Volume Parameters in COVID-19 Patients'Blood

作　　者：李安明 高灵宝[1] 韩俊岭[1] 夏婷婷[1] 韩静[1] LI An-ming;GAO Ling-bao;HAN Jun-ling;XIA Ting-ting;HAN Jing(Taizhou People's Hospital,Taizhou Jiangsu 225300,China)

机构地区：[1]泰州市人民医院,江苏泰州225300

出　　处：《泰州职业技术学院学报》2021年第1期58-60,共3页Journal of Taizhou Polytechnic College

摘　　要：目的观察新型冠状病毒肺炎患者血液中RDW-SD、RDW-CV和MCV三种红细胞体积参数的变化。方法以确诊为新型冠状病毒肺炎患者17例作为病例组,64例普通肺部感染患者作为对照组,比较两组患者的RDW-SD、RDW-CV和MCV均值。结果新型冠状病毒肺炎组的RDW-SD、RDW-CV和MCV均值分别为39.7、12.3和88.5;普通肺部感染组的RDW-SD、RDW-CV和MCV均值分别为43.7、13.7和88.4;病例组与对照组比较RDW-SD(t=3.168,P=0.002),RDW-CV(t=3.990,P<0.001)有统计学差异,MCV(t=0.038,P=0.970)无统计学差异;RDW-SD、RDW-CV和三种红细胞体积参数联合检测的ROC曲线下面积分别为0.674、0.677和0.712。结论新型冠状病毒肺炎患者血液中红细胞体积参数RDW-SD和RDW-CV在发病过程中有明显变化,而普通肺部感染患者血液中红细胞体积参数在发病过程中变化不明显;RDW-SD、RDW-CV和MCV这三种红细胞体积参数联合检测可以辅助鉴别诊断新型冠状病毒肺炎与普通肺部感染。Objective To observe the changes of volume parameters of three RBC RDW-SD,RDW-CV and MCV,in COVID-19 patients'blood.Methods 17 COVID-19 patients were selected as case group and 64 pa⁃tients with common pulmonary infection as control group.The mean values of RDW-SD,RDW-CV and MCV were compared between two groups.Results The means of COVID-19 group's RDW-SD,RDW-CV and MCV were 39.7,12.3 and 88.5 respectively.The means of common lung infection group's RDW-SD,RDWCV and MCV were 43.7,13.7 and 88.4 respectively,and there was a significant difference between the case group's and the control group's RDW-SD(t=3.168,P=0.002)and RDW-CV(t=3.990,P<0.01).There was no signifi⁃cant difference between the case group's and the control group's MCV(t=0.038,P=0.970).The area under ROC curve of RDW-SD,RDW-CV and combined detection of three RBC volume parameters was 0.674,0.677 and 0.712,respectively.Conclusion The RBC volume parameters RDW-SD and RDW-CV in COVID-19 patients'blood has obvious change in the process of disease,while the RBC volume parameters in common lung infection patients’blood has no obvious change in the process of disease.COVID-19 and common lung infection can be identified by combined detection of three RBC volume parameters,RDW-SD,RDW-CV and MCV.

关 键 词：COVID-19 肺部感染 RDW-SD RDW-CV MCV 

分 类 号：R511[医药卫生—内科学]