甲状腺功能异常对自发性早产产妇负面情绪的影响  

Effect of abnormal thyroid function on negative emotion of spontaneous preterm delivery

作　　者：李宁 冯玲[2] 周舟 LI Ning;FENG Ling;ZHOU Zhou(Department of Laboratory Medicine,the Third People′s Hospital of Ganzhou City,Jiangxi Province,Ganzhou341000,China;Department of Obstetrics and Gynecology,Xinfeng County People′s Hospital,Jiangxi Province,Xinfeng341000,China)

机构地区：[1]江西省赣州市第三人民医院检验科,江西赣州341000 [2]江西省信丰县人民医院妇产科,江西信丰341000

出　　处：《中国当代医药》2021年第12期147-149,153,共4页China Modern Medicine

基　　金：江西省赣州市指导性科技计划任务(GZ2017ZSF 258)。

摘　　要：目的探讨甲状腺功能异常对自发性早产产妇负面情绪的影响。方法选取2016年1月~2019年12月于信丰县人民医院就诊的98例自发性早产产妇,产后进行游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺激素(TSH)检测,采用汉密尔顿抑郁量表(HAMD)-24项,汉密尔顿焦虑量表(HAMA)评估负面情绪,比较FT3、FT4、TSH正常者和异常者的HAMD、HAMA评分,分析甲状腺功能异常对焦虑、抑郁情绪的影响。结果FT3、FT4正常与异常水平的自发性早产产妇的HAMD和HAMA评分比较,差异无统计学意义(P>0.05)。TSH异常水平的自发性早产产妇HAMD和HAMA评分高于TSH正常者,差异有统计学意义(P<0.05)。FT3、FT4异常与正常水平的自发性早产产妇抑郁情绪检出率和焦虑情绪检出率比较,差异无统计学意义(P>0.05)。TSH异常水平的自发性早产产妇抑郁情绪检出率和焦虑情绪检出率均高于TSH正常者,差异有统计学意义(P<0.05)。结论TSH是自发性早产产妇负面情绪的影响因素,TSH异常的自发性早产产妇更易出现焦虑情绪和抑郁情绪。应引起临床医生的重视,及早关注和预防,对其进行针对性心理疏导和干预。Objective To investigate the effect of abnormal thyroid function on negative emotion of spontaneous premature parturient.Methods A total of 98 cases of spontaneous preterm delivery in Xinfeng County People′s Hospital from January 2016 to December 2019 were selected.Free triiodothyronine(FT3),free thyroxine(FT4)and thyroid stimulating hormone(TSH)were detected postpartum.The Hamilton depression scale(HAMD)-24 items and the Hamilton anxiety scale(HAMA)were used to assess negative emotions.The HAMD and HAMA scores of patients with normal and abnormal FT3,FT4 and TSH were compared,the influence of abnormal thyroid function on anxiety and depression was analyzed.Results There were no statistical significances in HAMD and HAMA scores of spontaneous preterm parturiums with normal and abnormal FT3 and FT4 levels(P>0.05).HAMD and HAMA scores of spontaneous preterm parturials with abnormal TSH were higher than those with normal TSH,and the differences were statistically significant(P<0.05).There was no statistical significance in the detection rate of depression and anxiety between abnormal FT3 and FT4 levels and normal levels of spontaneous preterm delivery(P>0.05).The detection rates of depression and anxiety in spontaneous preterm parturiums with abnormal TSH level were higher than those in normal TSH group,with statistical significances(P<0.05).Conclusion TSH is an influential factor for the negative emotions of spontaneous preterm delivery women,and the women with abnormal spontaneous preterm delivery are more likely to have anxiety and depression.It should arouse the clinician′s attention,early attention and prevention,to carry on the targeted psychological counseling and intervention.

关 键 词：甲状腺激素水平 自发性早产 负面情绪 焦虑 抑郁 

分 类 号：R714.25[医药卫生—妇产科学]