甲状腺手术患者达克罗宁辅助利多卡因表麻抑制气管插管反应的效果  

Inhibition of stress response to endotracheal intubation under topical anesthesia assisted by dyclonine with lidocaine in patients undergoing thyroid surgery

作　　者：王恒所 胡成云 李传耀 唐朝亮 WANG Heng-suo;HU Cheng-yun;LI Chuan-yao(Guoyang People's Hospital,Bozhou 233600,Anhui;The First Affiliated Hospital of USTC,Hefei 230001,Anhui)

机构地区：[1]涡阳县人民医院麻醉科,安徽亳州233600 [2]中国科学技术大学附属第一医院麻醉科,安徽合肥230001

出　　处：《安徽卫生职业技术学院学报》2021年第2期32-34,共3页Journal of Anhui Health Vocational & Technical College

基　　金：中央高校基本科研业务费专项资金资助(编号:WK9110000044)。

摘　　要：目的:探讨达克罗宁辅助利多卡因表面麻醉预防甲状腺手术患者全麻插管时心血管反射的临床效果。方法:择取全麻下行甲状腺手术患者40例,性别不限,年龄18~76岁,ASA分级Ⅰ~Ⅱ级,根据随机数字表法将患者分为对照组和实验组,每组20例。对照组患者只进行利多卡因表面进麻醉,实验组患者在利多卡因表面麻醉基础上辅助用达克罗宁。分别观察两组患者诱导前(T0)、使用利多卡因表面麻醉时(T1)、插管后即刻(T2)时的SBP、DBP和HR。记录麻醉恢复期并发症发生情况和患者对麻醉效果的满意度评分。结果:与对照组比较,实验组患者在T1和T2时SBP、DBP 和HR降低,拔除气管导管时呛咳的例数减少,患者对麻醉的满意度评分升高(P<0.05)。结论:达克罗宁辅助利多卡因表面麻醉用于甲状腺手术患者可维持血流动力学平稳,降低应激反应,减少恢复期并发症,提高患者对麻醉效果的满意度。Objective:To study the clinical effect of dyclonine assisted lidocaine topical anesthesia in preventing cardiovascular responses during general anesthesia intubation in thyroid surgery.Methods:Forty patients scheduled for thyroid surgery under general anesthesia,all genders,ages 18 to 76 years,ASA classⅠ-Ⅱ,were randomly allocated to receive either topical anesthesia with lidocaine (group C),or receive dyclonine combined with topical anesthesia with lidocaine (group E).Systolic blood pressure (SBP),diastolic blood pressure (DBP) and Heart rate,were recorded at three time points:before induction (T0),after topical anesthesia with lidocaine (T1),and immediately after intubation (T2);The incidence of complications during anesthesia recovery period and the patients’ satisfaction score of anesthesia were all recorded.Results:Compared with group C,SBP,DBP and HR were significantly decreased at T1 and T2,the number of cases of cough during extubationwas significantly decreased,and score for patients’ satisfaction with anesthesia was significantly increased in group E (P<0.05).Conclusion:Dyclonine assisted topical anesthesia with lidocaine in patients undergoing thyroid surgery can significantly maintain hemodynamics stability,reduce stress response,reduce complications during recovery,and improve patients’ satisfaction with anesthesia.

关 键 词：达克罗宁 利多卡因 气管插管 心血管反应 甲状腺手术 

分 类 号：R653[医药卫生—外科学]