2010年-2019年浙江省人民医院629014例患者梅毒血清学检测结果分析  

Serological analysis of syphilis in 629014 patients in Zhejiang Provincial People’s Hospital from 2010 to 2019

作　　者：董晓燕 徐鑫宇 杨芳芳 沈宇欢 葛玉梅[4] DONG Xiao-yan;XU Xin-yu;YANG Fang-fang;SHEN Yu-huan;GE Yu-mei(The Second Medical College,Zhejiang Chinese Medical University,Hangzhou,Zhejiang 310053,China)

机构地区：[1]浙江中医药大学第二临床医学院,浙江杭州310053 [2]新疆医科大学克拉玛依学院,新疆克拉玛依834000 [3]温州医科大学检验医学院生命科学院,浙江温州325035 [4]浙江省人民医院临床医学检验中心杭州医学院附属人民医院,浙江杭州310014

出　　处：《中国卫生检验杂志》2021年第7期866-869,共4页Chinese Journal of Health Laboratory Technology

基　　金：浙江省医药卫生科技项目(2019KY013);浙江省人民医院优秀青年人员科研启动基金(ZRY2018B004);浙江省自然科学基金面上项目(LY20H200008)。

摘　　要：目的了解2010年-2019年浙江省人民医院患者梅毒血清学检测情况,为梅毒的监控、确诊提供实验室依据。方法回顾性分析浙江省人民医院2010年-2019年门诊、住院、住院急诊和体检血清学检测梅毒患者的临床病史和检验结果。结果2010年-2019年血清学梅毒检测者共629014例,其中男性267182例,女性361832例,男、女比例约为3∶4,梅毒检测阳性患者共17219例,总阳性率为2.74%,梅毒检测女性阳性患者9217例,阳性率为2.55%,梅毒检测男性阳性患者8002例,阳性率为2.99%。2011年-2019年,年梅毒检测增长率分别为24.45%、15.78%、7.07%、8.84%、5.55%、11.59%、53.17%、-3.23%、7.00%;年梅毒病例增长率分别为21.20%、14.38%、5.94%、9.16%、-1.51%、2.27%、59.65%、-19.30%、3.21%。结论梅毒检测人数逐年增加提示梅毒筛查在浙江地区越来越受到重视,对梅毒的防控、诊治具有重要作用。梅毒病例数在浙江地区依旧处于较高水平,提示医疗机构和疾病预防控制机构等需进一步加大对梅毒的诊治和防控。Objective To investigate the serological results of syphilis in Zhejiang People’s Hospital from 2010 to 2019,so as to provide laboratory evidence for surveillance and diagnosis of syphilis.Methods The clinical history and serological examination results of syphilis patients of outpatient,inpatient,inpatient emergency,physical examination in Zhejiang People’s Hospital from 2010 to 2019 were conducted for retrospective analysis.Results From 2010 to 2019,629014 patients were serologically tested for syphilis,including 267182 males and 361832 females,with male to female ratio to 3∶4.A total of 17219 patients were positive,with a total positive rate of 2.74%,9217 females were positive,with a positive rate of 2.55%,and 8002 males were tested positive,with a positive rate of 2.99%.From 2011 to 2019,the annual growth rate of syphilis examination was 24.45%,15.78%,7.07%,8.84%,5.55%,11.59%,53.17%,-3.23%,and 7.00%,respectively.The annual growth rates of syphilis cases were 21.20%,14.38%,5.94%,9.16%,-1.51%,2.27%,59.65%,-19.30%,and 3.21%respectively.Conclusion The increasing number of syphilis examination indicated that syphilis screening is paid more and more attention in Zhejiang,which plays an important role in prevention,diagnosis and treatment of syphilis.The number of syphilis cases in Zhejiang is still at a high level,suggesting that medical institutions and disease prevention and control institutions need to further strengthen the diagnosis,treatment,prevention and control of syphilis.

关 键 词：梅毒 血清学 发病率 分布特征 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]