胰岛素泵皮下注射和多次胰岛素皮下注射治疗妊娠期糖尿病的疗效比较  

Comparison of the Curative Effect of Insulin Pump Subcutaneous Injection and Multiple Insulin Subcutaneous Injections in the Treatment of Gestational Diabetes

作　　者：何华平 HE Huaping(Department of Obstetrics,People's Hospital of Taishan City,Taishan,Guangdong Province,529200 China)

机构地区：[1]广东省台山市人民医院产科,广东台山529200

出　　处：《糖尿病新世界》2021年第5期93-95,共3页Diabetes New World Magazine

摘　　要：目的分析经胰岛素泵开展皮下注射与多次皮下注射胰岛素对妊娠期糖尿病(GDM)的疗效。方法将2017年1月—2019年8月该院收治的GDM患者共72例为研究对象,依据随机数表法分成对照组(多次皮下注射胰岛素)和观察组(经胰岛素泵开展皮下注射),各36例,比较两组治疗前后空腹血糖(FPG)、餐后2 h血糖(2 hPG)、糖化血红蛋白(HbA1c)、胰岛素用量、血糖达标时间、低血糖及并发症情况。结果治疗前,两组FPG、2 hPG以及HbA1c水平对比差异无统计学意义(P>0.05);治疗后5 d,观察组FPG、2 hPG水平均低于对照组,胰岛素用量少于对照组,血糖达标所需天数短于对照组,差异有统计学意义(P<0.05)。观察组妊高症、早产、羊水过多、产后出血以及巨大儿等并发症出现少于对照组,差异有统计学意义(P<0.05)。结论和多次皮下注射胰岛素对比,予以GDM患者胰岛素泵皮下注射能更好地控制其血糖水平,减少低血糖和母婴并发症出现,效果更佳。Objective To analyze the efficacy of subcutaneous injection of insulin through an insulin pump and multiple subcutaneous injections of insulin on gestational diabetes(GDM).Methods A total of 72 patients with GDM admitted to the hospital from January 2017 to August 2019 were selected as the research objects.According to the random number table,they were divided into a control group(multiple subcutaneous injections of insulin)and an observation group(subcutaneous injections via an insulin pump),36 cases each,and the two were compared.Before and after treatment,fasting blood glucose(FPG),2 h postprandial blood glucose(2 hPG),glycosylated hemoglobin(HbA1c),insulin dosage,blood glucose up-to-standard time,hypoglycemia and complications in the group.Results Before treatment,there was no statistically significant difference between the two groups of FPG,2 hPG levels(P>0.05);5 d after treatment,the FPG,2 hPG and HbA1c levels of the observation group were lower than those of the control group,insulin consumption was less than that of the control group,and blood glucose was up to standard,the number of days required was shorter than that of the control group,and the difference was statistically significant(P<0.05).Complications such as pregnancy-induced hypertension,premature delivery,hyperamniotic fluid,postpartum hemorrhage,and macrosomia in the observation group were less than those in the control group,and the difference was statistically significant(P<0.05).Conclusion Compared with multiple subcutaneous injections of insulin,subcutaneous injection of insulin pump in GDM patients can better control their blood glucose levels,reduce hypoglycemia and maternal and infant complications,and have better results.

关 键 词：妊娠期糖尿病 胰岛素 皮下注射 胰岛素泵 母婴并发症 

分 类 号：R714.256[医药卫生—妇产科学]