中年男性2型糖尿病不同体型患者性激素与体脂分布的相关性分析  

Analysis of the correlation between sex hormones and body fat distribution in middle-aged male patients with diabetes mellitus type 2 and different somatotypes

作　　者：黄建皓[1] 卢杰 玉颜庆[1] 余劲明[1] HUANG Jian-hao;LU Jie;YU Yan-qing(Department of Endocrinology and Metabolism, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China)

机构地区：[1]广西壮族自治区人民医院内分泌代谢科,南宁530021

出　　处：《中国临床新医学》2021年第4期363-367,共5页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：广西科学研究与技术开发计划项目(编号:桂科攻15277013);广西卫健委科研课题(编号:Z2016587)。

摘　　要：目的分析中年男性2型糖尿病不同体型患者性激素水平与体脂分布的相关性。方法选择2018-05~2019-11广西壮族自治区人民医院内分泌代谢科收治的中年男性2型糖尿病患者50例,根据体质量指数(BMI)将其分为体重正常组(A组,BMI=18.5~23.9 kg/m2,n=14),超重组(B组,24.0~27.9 kg/m2,n=20)和肥胖组(C组,≥28.0 kg/m2,n=16)。比较三组患者的体型、体脂分布、血脂和性激素水平,分析性激素水平与体脂分布的相关性。结果三组腰围比较差异有统计学意义(P<0.05),其中C组腰围显著大于A组和B组(P<0.05),B组腰围也显著大于A组(P<0.05)。三组甘油三酯(TG)水平比较差异有统计学意义(P<0.05),其中A组TG水平显著低于B组和C组(P<0.05)。三组总睾酮(TT)水平比较差异有统计学意义(P<0.05),其中C组TT水平显著低于A组(P<0.05)。三组全身脂肪比例、“Android区域”脂肪比例以及A/G值比较差异有统计学意义(P<0.05),其中C组的全身脂肪比例、“Android区域”脂肪比例显著高于A组和B组(P<0.05),A/G值显著高于A组(P<0.05)。Pearson相关分析结果显示,TT与腰围、黄体生成素(LH)、“Android区域”脂肪比例、A/G值呈负相关(P<0.05)。结论中年男性2型糖尿病患者的TT水平与体脂分布密切相关,内脏脂肪蓄积是TT水平下降的重要危险因素。Objective To analyze the correlation between the levels of sex hormones and body fat distribution in middle-aged male patients with diabetes mellitus type 2 and different somatotypes.Methods Fifty middle-aged male patients with diabetes mellitus type 2 admitted to the Department of Endocrinology and Metabolism,the People′s Hospital of Guangxi Zhuang Autonomous Region from May 2018 to November 2019 were selected and divided into the normal weight group(group A,BMI=18.5-23.9 kg/m2,n=14),the overweight group(group B,24.0-27.9 kg/m2,n=20)and the obesity group(group C,≥28.0 kg/m2,n=16)according to different levels of Body Mass Index(BMI).The somatotypes,body fat distribution,blood fat and sex hormone levels were compared among the three groups,and the correlation between sex hormone levels and body fat distribution was analyzed.Results There was statistically significant difference in waist circumference among the three groups(P<0.05),in which group C had significantly larger waist circumference than group A and group B(P<0.05),and group B had significantly larger waist circumference than group A(P<0.05).There was statistically significant difference in the level of triglyceride(TG)among the three groups(P<0.05),in which group A had significantly lower TG level than group B and group C(P<0.05).There was statistically significant difference in the level of total testosterone(TT)among the three groups(P<0.05),in which group C had significantly lower TT level than group A(P<0.05).There were statistically significant differences in the proportion of body fat,the proportion of fat in the“Android area”and the A/G value(P<0.05)among the three groups(P<0.05),in which group C had significantly higher proportion of body fat and higher proportion of fat in the“Android area”than group A and group B(P<0.05),and group C had significantly higher A/G value than group A(P<0.05).The results of Pearson correlation analysis showed that TT was negatively correlated with waist circumference,luteinizing hormone(LH),the proportio

关 键 词：2型糖尿病 体脂分布 性激素 

分 类 号：R587.1[医药卫生—内分泌]