3D SERS substrate based on nanocone forests for miRNA detections  

基于纳米锥森林的三维SERS基底检测miRNA

作　　者：LI Ruirui LI Yongwei XIONG Jijun 李锐锐;李永伟;熊继军(中北大学仪器科学与动态测试教育部重点实验室,山西太原030051)

机构地区：[1]Key Laboratory of Instrumentation Science and Dynamic Measuremen(North University of China),Ministry of Education, Taiyuan 030051, China

出　　处：《Journal of Measurement Science and Instrumentation》2021年第2期226-231,共6页测试科学与仪器（英文版）

摘　　要：Surface-enhanced Raman scattering(SERS)is a powerful technology for obtaining vibrational information from molecules that present in different chemical or biological environments.This paper presents a 3D SERS substrate based on nanocone forests.The substrates are prepared by using plasma treatment technique,which is a simple,fast and high-throughput approach.The SERS substrate based on nanocone forests exhibits high sensitivity.In the experiment,miRNA with a concentration as low as 10-10 M can be achieved.Meanwhile,the proposed SERS substrate shows a high uniformity over a large area.These experimental results demonstrate great potential of the 3D SERS substrate in wide applications.

关 键 词：surface-enhanced Raman scattering(SERS)substrates nanocone forests three-dimensional hot spots miRNA detection 

分 类 号：O657.37[理学—分析化学] Q503[理学—化学]