阴道超声联合血清β-hGG、P检测诊断未破裂异位妊娠效能  

Value of vaginal ultrasound combined with-human chorionic gonadotropin(β-HCG)and progesterone levels for diagnosing unruptured ectopic pregnancy

作　　者：倪梁红 童陶然[1] 胡海燕[1] 袁小庆 NI lianghong;TONG Taoran;HU Haiyan;YUAN Xiaoqing(Tongling People's Hospital,Anhui Province,244000)

机构地区：[1]安徽省铜陵市人民医院,244000

出　　处：《中国计划生育学杂志》2021年第3期524-527,532,共5页Chinese Journal of Family Planning

摘　　要：目的:探讨阴道超声联合血清β-人绒毛膜促性腺激素(β-hGG)、孕酮(P)检测在未破裂异位妊娠诊断效能。方法:选取2016年6月—2019年9月本院治疗的未破裂异位妊娠患者81例为观察组,同期正常孕妇81例为对照组。两组均行阴道超声检查,包括阻力指数(RI)、脉搏指数(PI)]及血清β-hGG、P,给予观察组对应治疗。采用受试者工作特征曲线(ROC)比较阴道超声、血清生化指标诊断未破裂异位妊娠效能。结果:与对照组比,观察组的脉搏指数(PI)和阻力指数(RI)增高,β-hGG及P水平降低(均P<0.05)。logistic回归分析显示,入院时RI、PI、β-hGG和P可影响异位妊娠发生,其中RI和PI是独立危险因素(P<0.05),β-hGG和P是保护因素(P<0.05)。RI、PI、β-hGG、P联合检测诊断异位妊娠的曲线下面积0.978,敏感度(98.8%)、特异性(97.5%)最高。治疗后观察组RI降低,β-hGG、P增高(均P<0.05)。结论:未破裂异位妊娠患者体内血清β-hGG、P水平异常表达,联合阴道超声共同检测可提高未破裂异位妊娠诊断效率。Objective:To investigate the value of vaginal ultrasound combined withβ-human chorionic gonadotropin(β-HCG)and progesterone(P)levels for diagnosing unruptured ectopic pregnancy.Methods:81 patients with unruptured ectopic pregnancy were selected in study group,and another 81 normal pregnant women were selected in control group from June 2016 to September 2019.The patients in the two groups were given vaginal ultrasonography examination for evaluating their the blood flow parameters,such as resistance index(RI)and pulse index(PI),and their serum levels ofβ-HCG and P were detected.Then the patients in the study group were further treated.Receiver operating characteristic curve(ROC)was used to compare the efficiency of the blood flow parameters by vaginal ultrasonography and the detection of the serum biochemical indexes for diagnosing unruptured ectopic pregnancy.Results:The values of PI and RI of the patients in the study group were significant higher than those of the patients in the control group,but the levels ofβ-HCG and P of the patients in the study group were significant lower(all P<0.05).Logistic regression analysis showed that RI and PI values andβ-HCG and P levels of the patients when hospitalized could affect the occurrence of ectopic pregnancy,in which,RI and PI values were the independent risk factors(P<0.05),andβ-HCG and P levels were the protective factors(P<0.05).The area under the curve of combined of RI and PI examination andβ-HCG and P levels detection for diagnosing ectopic pregnancy was 0.978,which’s sensitivity(98.8%)and specificity(97.5%)were the highest.After treatment,the RI value of the patients in the study group had decreased significantly and theβ-HCG and P levels had increased significantly(all P<0.05).Conclusion:The levels of serumβ-HCG and P of the patients with unruptured ectopic pregnancy are abnormally.The combination of RI and PI examination andβ-HCG and P levels for diagnosing ectopic pregnancy can improve the diagnostic efficiency,which can provide guidance in clini

关 键 词：未破裂异位妊娠 阴道超声 阻力指数 脉搏指数 Β-人绒毛膜促性腺激素 孕酮 

分 类 号：R714.22[医药卫生—妇产科学]