人工流产术后即刻放置两种不同IUD应激反应分析  

Stress response in who had post abortion intrauterine devices insertion

作　　者：乔明霞[1] 张爽爽 杨燕 QIAO Mingxia;ZHANG Shuangshuang;YANG Yan(Zaozhuang Maternity and Child Health Care Hospital,Shandong Province,277100)

机构地区：[1]山东省枣庄市妇幼保健院,277100

出　　处：《中国计划生育学杂志》2021年第4期752-754,共3页Chinese Journal of Family Planning

摘　　要：目的:探讨人工流产术后即刻放置两种不同IUD应激反应情况。方法:选取2017年7月—2019年10月于本院实施人工流产术440例,根据术后是否置器及其放置类型分为未置器对照组(n=120)、置入吉妮致美IUD组(n=160)和花式IUD组(n=160)。检测3组妇女术前30min(T0)及其术后30min(T1)、6h(T2)、24h(T3)、48h(T4)血清皮质醇(Cor)、丙二醛(MDA)、促肾上腺皮质激素(ACTH)、去甲肾上腺素(NA)、血管紧张素Ⅱ(Ang-Ⅱ)等应激反应因子水平。结果:3组血清应激因子水平T0时无差异(P<0.05),T1时均高于其他时刻(P<0.05)。吉妮致美IUD组、花式IUD组在T1、T2、T3、T4时刻血清Cor、MDA、ACTH、NA及Ang-Ⅱ均高于对照组(P均<0.05),但两组间无差异(P均>0.05)。结论:流产术后即刻放置不同IUD均会对女性机体产生应激反应,但观察的两种IUD未见差异。提示临床须引起重视。Objective:To explore the stress response status of the women after two intrauterine devices(IUD)inserted post abortion immediately.Methods:440 women with induced abortion were selected and were divided into control group(120 women without IUD inserted),group A(160 women with Ginny IUD inserted),and group B(160 women with HCu IUD inserted)from July 2017 to October 2019.The serum stress response indexes levels,such as cortisol(cor),malondialdehyde(MDA),adrenocorticotropic hormone(ACTH),norepinephrine(NA)and angiotensinⅡ(Ang-Ⅱ)of the women in the three groups were measured at 30 min before operation(T0),30 min after operation(T1),6 h after operation(T2),24 h after operation(T3),and 48 h after operation(T4),respectively.Results:There was no significant differences in the serum stress factor levels of the women at T0 among the three groups(P>0.05),and the serum stress factor levels of the women in the three groups at T1 were significant higher than those at other time(P<0.05).The levels of serum Cor,MDA,ACTH,NA,and Ang-Ⅱof the women in group A and group B at T1,T2,T3,T4 were significant higher than those of the women in group C(all P<0.05),but those of the women had no significant differences between group A and group B(P>0.05).Conclusion:Two IUD inserted immediately after abortion will lead to the stress response of the women,but there is no significant different in degree of the stress response of the women between the two IUD,so both IUD should be paid more attention to in clinical practice.

关 键 词：人工流产术 宫内节育器 吉妮致美 花式宫内节育器 应激反应 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]