角膜缘组织移植治疗角膜缘缺损的效果  

Effect of corneal limbal tissue transplantation in the treatment of corneal limbal defect

作　　者：于娇 YU Jiao(Department of Glaucoma,Fushun Ophthalmopathy Hospital,Liaoning Province,Fushun113000,China)

机构地区：[1]辽宁省抚顺市眼病医院青光眼科,辽宁抚顺113000

出　　处：《中国当代医药》2021年第11期151-154,共4页China Modern Medicine

摘　　要：目的探讨角膜缘组织移植治疗角膜缘缺损的有效性。方法选取2018年5月~2019年5月抚顺市眼病医院收治的112例角膜缘缺损患者为研究对象。全部患者均为单只患眼,根据随机数字表法分为研究组(n=56)与对照组(n=56)。对照组应用浅表角膜部分切除,研究组应用角膜缘组织移植治疗。比较两组患者的炎症反应情况、治愈率、复发率、满意度及生活质量。结果研究组患者的炎症反应发生率低于对照组,差异有统计学意义(P<0.05);研究组患者的治愈率高于对照组,治疗后复发率低于对照组,差异有统计学意义(P<0.05);研究组患者的治疗满意度及生活质量评分高于对照组,差异有统计学意义(P<0.05)。结论在眼表疾病的临床治疗过程中应用角膜缘组织移植术,可以有效提高患者的临床治疗效果,减少患者的复发率,有效提高患者视力,提高患者的生活质量,且患者的治疗满意度较高,临床效果理想,临床上应当进一步推广应用。Objective To explore the effectiveness of corneal limbal tissue transplantation in the treatment of corneal limbal defect.Methods A total of 112 patients with corneal limbal defect who were admitted to Fushun Ophthalmopathy Hospital from May 2018 to May 2019 were selected as the research subjects.All patients had a single affected eye and were divided into study group(n=56)and control group(n=56)according to the random number table method.The superficial cornea was partially excised in the control group,while the corneal limbal tissue graft was applied in the study group.The inflammatory response,clinical cure rate,recurrence rate,satisfaction degree and quality of life of the two groups were compared.Results The incidence of inflammatory reaction in the study group was lower than that in the control group,the difference was statistically significant(P<0.05).The cure rate of patients in the study group was higher than that in the control group,and the recurrence rate after treatment was lower than that in the control group,the differences were statistically significant(P<0.05).The treatment satisfaction and quality of life score of patients in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The application of corneal limbal tissue transplantation in the clinical treatment of ocular surface diseases can effectively improve the clinical treatment effect of patients,reduce the recurrence rate of patients,effectively improve the vision of patients,improve the quality of life of patients,and the satisfaction of patients with treatment is high,clinical effect is ideal,so it should be further promoted and applied clinically.

关 键 词：角膜缘 组织移植 眼表疾病 有效性 

分 类 号：R246.8[医药卫生—针灸推拿学]