普拉洛芬滴眼液治疗白内障术后炎症的有效性分析  

Effectiveness analysis of Pranoprofen Eye Drops in the treatment of inflammation after cataract surgery

作　　者：高世凯 李海波 GAO Shi-kai;LI Hai-bo(Department of Ophthalmology,Affiliated Hospital of Chifeng College,Inner Mongolia Autonomous Region,Chifeng024000,China)

机构地区：[1]赤峰学院附属医院眼科,内蒙古赤峰024000

出　　处：《中国当代医药》2021年第11期158-161,共4页China Modern Medicine

摘　　要：目的探讨并分析普拉洛芬滴眼液治疗白内障术后炎症的有效性。方法选取2015年1月~2020年6月于赤峰学院附属医院就诊的80例白内障术后炎症患者作为研究对象。采用随机数字表法将其分为对照组和观察组,每组各40例。对照组患者均采用氟米龙滴眼液治疗,观察组患者均采用普拉洛芬滴眼液治疗。比较两组患者的术后炎症指标水平、眼部症状评分以及眼压变化情况。结果治疗4周后,两组患者的白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)及C反应蛋白(CRP)水平均低于治疗前,且观察组患者的IL-6、TNF-α及CRP水平均低于对照组,差异有统计学意义(P<0.05)。治疗1周后,两组患者的眼部症状评分均低于治疗前,差异有统计学意义(P<0.05);治疗3周后,两组患者的眼部症状评分均低于治疗1周后,差异有统计学意义(P<0.05);治疗4周后,两组患者的眼部症状评分均低于治疗3周后,差异有统计学意义(P<0.05);治疗1、3、4周后,观察组患者的眼部症状评分均低于对照组,差异有统计学意义(P<0.05)。治疗1周后,两组患者的眼压水平均低于治疗前,差异有统计学意义(P<0.05);治疗3周后,两组患者的眼压水平均低于治疗1周后,差异有统计学意义(P<0.05);治疗4周后,两组患者的眼压水平均低于治疗3周后,差异有统计学意义(P<0.05);治疗1、3、4周后,观察组患者的眼压水平均低于对照组,差异有统计学意义(P<0.05)。结论普拉洛芬滴眼液能够有效缓解患者的术后炎症反应,可以有效改善患者的眼部症状,降低眼压,提高眼部功能,值得推广。Objective To explore and analyze the effectiveness of Pranoprofen Eye Drops in the treatment of postoperative inflammation of cataract.Methods From January 2015 to June 2020,a total of 80 patients with postoperative cataract inflammation treated in the Affiliated Hospital of Chifeng College were selected as the research subjects.They were divided into control group and observation group by the random number table method,with 40 cases in each group.The patients in the control group were treated with Fluorometholone Eye Drops,and the patients in the observation group were treated with Pranoprofen Eye Drops.The postoperative inflammatory index levels,eye symptom scores and changes in intraocular pressure were compared between the two groups.Results After 4 weeks of treatment,the levels of interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)and C-reactive protein(CRP)in the two groups were lower than before treatment,and the levels of IL-6,TNF-αand CRP in observation group were lower than those in the control group,the differences were statistically significant(P<0.05).After 1 week of treatment,the ocular symptom scores of the two groups were lower than those before treatment,the differences were statistically significant(P<0.05);After 3 weeks of treatment,the ocular symptom scores of the two groups were lower than those after 1 week of treatment,the differences were statistically significant(P<0.05).After 4 weeks of treatment,the ocular symptom scores of the two groups were lower than those after 3 weeks of treatment,the differences were statistically significant(P<0.05).After 1,3 and 4 weeks of treatment,eye symptom scores in observation group were all lower than those in the control group,the differences were statistically significant(P<0.05).After 1 week of treatment,intraocular pressure levels in the two groups were lower than those before treatment,the differences were statistically significant(P<0.05).After 3 weeks of treatment,the intraocular pressure levels of the two groups were lower than those after 1 we

关 键 词：普拉洛芬滴眼液 白内障 术后炎症 应用效果 

分 类 号：R766.1[医药卫生—耳鼻咽喉科]