三种骨替代材料修复即刻种植下颌后牙区周围骨缺损的比较  

Comparison of three kinds of bone replacement materials in the treatment of bone defects around the mandibular posterior teeth with immediate implantation

作　　者：肖莎 高承志[1] 周冬平[1] Xiao Sha;Gao Chengzhi;Zhou Dongping(Department of Stomatology,Peking University People’s Hospital,Beijing 100044,China)

机构地区：[1]北京大学人民医院口腔科,北京市100044

出　　处：《中国组织工程研究》2021年第34期5495-5500,共6页Chinese Journal of Tissue Engineering Research

摘　　要：背景:引导骨再生技术是解决种植区域骨缺损的有效方法,但是选择何种骨替代材料尚存有一定争议。目的:探讨不同材料应用于即刻种植下颌后牙区周围骨缺损的治疗效果。方法:选择2016年5月至2019年1月北京大学人民医院口腔科收治的138例下颌后牙区周围骨缺损患者,采用随机数字表法分3组,在即刻种植手术中分别植入Bio-Oss、Bone Plant、PerioGlas骨替代材料,每组46例。术后定期随访,比较3组种植体成功率、边缘骨水平、颊舌侧骨板宽度、垂直高度、牙周指标及患者满意度。研究获得北京大学人民医院伦理委员会批准,批准号:[伦审(R20160412)]。结果与结论:①术后12个月时,Bone Plant组种植体成功率高于PerioGlas组(P<0.05),其余组间两两比较差异无显著性意义(P>0.05);②Bio-Oss组、Bone Plant组术后6,12个月的边缘骨水平低于PerioGlas组(P<0.05),颊舌侧骨板宽度、垂直高度高于PerioGlas组(P<0.05);Bone Plant组术后6,12个月的垂直高度高于Bio-Oss组(P<0.05),两组间边缘骨水平、颊舌侧骨板宽度比较差异无显著性意义(P>0.05);③术后6,12个月时,3组间牙周探诊深度、探诊出血阳性率、牙龈指数比较差异均无显著性意义(P>0.05);④3组间患者满意度比较差异无显著性意义(P>0.05);⑤结果表明,Bio-Oss、PerioGlas、Bone Plant均具有一定诱导骨再生和成骨效果,Bio-Oss吸收慢但可维持一定骨板宽度,Bone Plant维持骨缺损垂直高度和空间稳定效果好,是较为理想的骨替代材料。BACKGROUND: Guided bone regeneration is an effective method to solve bone defects in the implant area, but the choice of bone replacement material is still controversial.OBJECTIVE: To investigate the treatment effect of different materials in the bone defects around the mandibular posterior teeth with immediate implantation. METHODS: From May 2016 to January 2019, 138 patients with bone defects around the mandibular posterior teeth, who were admitted to the Department of Stomatology in Peking University People’s Hospital, were selected. The patients were divided into three groups by random number table method, and were respectively implanted Bio-oss, Bone Plant, and PerioGlas bone replacement materials during immediate implantation, with 46 cases in each group respectively. Postoperative regular follow-up was conducted to compare the implant success rate, marginal bone level, buccal-lingual bone plate width, vertical height, periodontal index, and patient satisfaction in the three groups. This study had been approved by the Ethics Committee of Peking University People’s Hospital, approval No. [Ethical approval(R20160412)]. RESULTS AND CONCLUSION:(1) The success rate of implants in the Bone Plant group was higher than that in the PerioGlas group 12 months after PerioGlas operation(P < 0.05), but there was no significant difference between other groups(P > 0.05).(2) The edge bone levels of the Bio-OSS group and the Bone Plant group were lower than those in the PerioGlas group(P < 0.05). The width and vertical height of the buccal lingual bone plate were higher than those in the PerioGlas group(P < 0.05). The vertical height of the Bone Plant group at 6 and 12 months after operation was higher than that of the Bio-Oss group(P < 0.05), and there was no significant difference in the horizontal edge bone and the width of the buccal-lingual bone plate between the two groups(P > 0.05).(3) At 6 and 12 months after the operation, there was no significant difference in the depth of periodontal probe, the positive rate o

关 键 词：材料 口腔 骨再生 种植体 BIO-OSS Bone Plant PERIOGLAS 即刻种植 骨生成 满意度 

分 类 号：R459.9[医药卫生—治疗学] R318.08[医药卫生—临床医学]