血流向量成像技术评估阵发性房颤患者左室内压差的初步价值  

The preliminary value of vector flow mapping on assessment of left intraventricular pressure difference in patients with paroxysmal atrial fibrillation

作　　者：刘梅[1] 蔡宇燕 黄鹤[1] 钟玥[1] 王芳[1] LIU Mei;CAI Yuyan;HUANG He;ZHONG Yue;WANG Fang(Department of Cardiology,West China Hospital,Sichuan University,Chengdu 610041,P.R.China)

机构地区：[1]四川大学华西医院心内科,成都610041

出　　处：《生物医学工程学杂志》2021年第2期310-316,共7页Journal of Biomedical Engineering

摘　　要：本研究旨在应用基于血流向量成像(VFM)的相对压成像(RPI)技术探讨阵发性房颤(PAF)患者左室内压差(IVPD)的特点。纳入健康志愿者30例(对照组)及PAF患者20例(PAF组),行常规超声心动图和VFM检查。结果显示:①PAF组和对照组患者左室内心底-心尖压差峰值(B-A IVPD)在收缩期与舒张期均呈现收缩期一峰一谷、舒张期双峰双谷曲线;②基底段IVPD是B-A IVPD的主要组成部分,等容收缩期与收缩早期、收缩早期与收缩晚期、收缩晚期与等容舒张期的B-A IVPD均相关(P均<0.05);③PAF患者的等容收缩期、收缩早期、收缩晚期、等容舒张期的B-A IVPD、基底段IVPD均较对照组降低(P均<0.05)。研究表明PAF组及对照组的B-A IVPD模式相同,但PAF患者收缩期B-A IVPD与基底段IVPD明显减低。基于VFM的RPI技术可评价PAF患者左室IVPD,为评估PAF患者左室内血流动力学提供了一种可视化的量化方法。This study aims to explore the intraventricular pressure difference(IVPD)within left ventricle in patients with paroxysmal atrial fibrillation(PAF)by using the relative pressure imaging(RPI)of vector flow mapping(VFM).Twenty patients with paroxysmal atrial fibrillation(PAF)and thirty control subjects were enrolled in the study.Systolic and diastolic IVPD derived from VFM within left ventricle and conventional echocardiographic parameters were analyzed.It was found that the B-A IVPD of left ventricle in PAF patients showed the same pattern as controls—single peak and single valley during systole and double peaks and double valleys during diastole.Basal IVPD was the main component of base to apex IVPD(B-A IVPD).The isovolumetric systolic IVPD was associated with early systolic IVPD,early systolic IVPD was associated with late systolic IVPD,and late systolic IVPD was associated with isovolumic diastolic IVPD(all P<0.05).The B-A IVPD and basal IVPD during isovolumetric systole,early systole,late systole and isovolumetric diastole in PAF patients significantly decreased(all P<0.05).The study shows that the B-A IVPD pattern of the PAF group is the same as controls,but systolic B-A IVPD and basal IVPD are significantly reduced in PAF patients.VFM-derived RPI can evaluate left ventricular IVPD in PAF patients,providing a visually quantitative method for evaluating left ventricular hemodynamic mechanics in the patients with PAF.

关 键 词：血流向量成像 相对压成像 心室内压差 阵发性房颤 

分 类 号：R541.75[医药卫生—心血管疾病]