曼月乐与安宫黄体酮治疗围绝经期异常子宫出血的疗效比较  

The effect of Mirena and Angong Progesterone in the treatment of abnormal uterine hemorrhage during perimenopausal period

作　　者：孙东雪 SUN Dong-xue(First Hospital ofXifeng County,Tieling 112499,China)

机构地区：[1]辽宁省铁岭市西丰县第一医院,112499

出　　处：《中国实用医药》2021年第12期128-130,共3页China Practical Medicine

摘　　要：目的比较左炔诺孕酮宫内节育系统(商品名:曼月乐)与醋酸甲羟孕酮片(商品名:安宫黄体酮)治疗围绝经期异常子宫出血的临床疗效。方法68例围绝经期异常子宫出血患者,采取随机数字表法分为研究组和对照组,各34例。对照组采用安宫黄体酮治疗,研究组采用曼月乐治疗。对比两组治疗效果以及患者治疗前后月经时间、月经量。结果对照组治疗总有效率高于研究组,差异具有统计学意义(P<0.05)。治疗前,研究组月经时间为(9.56±2.34)d,月经量为(151.23±17.77)ml;对照组月经时间为(9.43±3.21)d,月经量为(153.13±17.86)ml;治疗后,研究组月经时间为(5.32±1.24)d,月经量为(23.78±7.54)ml;对照组月经时间为(6.89±1.24)d,月经量为(48.32±13.27)ml。治疗前,两组月经时间、月经量比较差异无统计学意义(P>0.05);治疗后,研究组月经时间短于对照组,月经量少于对照组,差异有统计学意义(P<0.05)。结论对围绝经期异常子宫出血患者采用曼月乐治疗,其治疗效果较为显著,可显著改善患者相关症状,临床可积极应用。Objective To compare the clinical efficacy of levonorgestrel intrauterine system(trade name: Mirena) and medroxyprogesterone acetate tablets(trade name: Angong Progesterone) in the treatment of abnormal uterine hemorrhage during perimenopausal period. Methods A total of 68 patients with abnormal uterine hemorrhage during perimenopausal period were divided into research group and control group according to random numerical table, with 34 cases in each group. The control group was treated with Angong Progesterone, and the research group was treated with Mirena. The therapeutic effect, menstrual time, menstrual volume before and after treatment were compared between the two groups. Results The total effective rate of the research group was higher than that of the control group, and the difference was statistically significant(P<0.05). Before treatment, the menstrual time and menstrual volume of the research group were(9.56±2.34) d and(151.23±17.77) ml, which were(9.43±3.21) d and(153.13±17.86) ml of the control group. After treatment, the menstrual time and menstrual volume of the research group were(5.32±1.24) d and(23.78±7.54) ml, which were(6.89±1.24) d and(48.32±13.27) ml of the control group. Before treatment, there was no statistically significant difference in menstrual time and menstrual volume between the two groups(P>0.05). After treatment, the menstrual time of the research group was shorter than that of the control group, and menstrual volume was less than that of the control group. All the difference was statistically significant(P<0.05). Conclusion Mirena has remarkable therapeutic effect on patients with abnormal uterine hemorrhage during perimenopausal period, and it can significantly improve the related symptoms of patients. It can be used in clinic.

关 键 词：左炔诺孕酮宫内节育系统 醋酸甲羟孕酮片 围绝经期 异常子宫出血 

分 类 号：R711.52[医药卫生—妇产科学]