2型糖尿病患者尿路感染危险因素的Meta分析  

Meta-analysis of risk factors of urinary tract infection in patients with type 2 diabetes

作　　者：种玉良 李晓刚[2] 张恩浩[2] 董秀哲[2] CHONG Yu-liang;LI Xiao-gang;ZHANG En-hao;DONG Xiu-zhe(Medical College of Yanbian University,Yanji,Jilin 133000,China)

机构地区：[1]延边大学医学院,吉林延吉133000 [2]延边大学附属医院泌尿外科,吉林延吉133000

出　　处：《现代预防医学》2021年第8期1524-1527,1536,共5页Modern Preventive Medicine

摘　　要：目的明确2型糖尿病患者发生尿路感染的危险因素,为预防尿路感染发生提供依据。方法计算机检索Cochrane图书馆、PubMed、Web of Science、中国知网、万方数据库和维普数据库,搜集自建库至2020年4月发表的相关文献,利用Endnote X9软件进行文献筛选,Rev Man 5.3软件进行meta分析。结果共纳入20篇文献,共计87 696例,提取14项危险因素,在年龄(MD=10.08,95%CI:7.61~12.54)、住院时间(MD=5.98,95%CI:3.41~8.55)、病程(OR=0.42,95%CI:0.20~0.90)、空腹血糖(OR=0.62,95%CI:0.46~0.84)、糖化血红蛋白(SMD=1.37,95%CI:0.93~1.81)、性别(OR=0.39,95%CI:0.28~0.55)、抗生素使用(OR=1.95,95%CI:1.21~3.12)、并发症(OR=3.01,95%CI:2.40~3.77)、留置尿管(OR=4.24,95%CI:2.59~6.93)方面有统计学意义(P<0.05)。结论年龄、住院时间、病程、空腹血糖、糖化血红蛋白、性别、抗生素使用、并发症、留置尿管是2型糖尿病患者发生尿路感染的危险因素。Objective To identify the risk factors of urinary tract infection in patients with type 2 diabetes and provide the basis for preventing urinary tract infection.Methods Cochrane Library,PubMed,Web of Science,CNKI,Wanfang Database and VIP Database were searched to collect the related literature published up to April 2020.Endnote X9 software was used for literature screening,and RevMan5.3 was used for Meta-analysis.Results A total of 20 articles were included involving 87696 samples,and 14 risk factors were extracted.Factors with statistical significance(P<0.05)including:age(MD=10.08,95%CI:7.61-12.54),length of hospital stay(MD=5.98,95%CI:3.41-8.55),course of disease(OR=0.42,95%CI:0.20-0.90),fasting blood glucose(OR=0.62,95%CI:0.46-0.84),glycosylated hemoglobin(SMD=1.37,95%CI:0.93-1.81),gender(OR=0.39,95%CI:0.28-0.55),antibiotic use(OR=1.95,95%CI:1.21-3.12),complications(OR=3.01,95%CI:2.40-3.77),indwelling catheter(OR=4.24,95%CI:2.59-6.93).Conclusion Age,length of stay,course of disease,fasting blood glucose,glycosylated hemoglobin,gender,antibiotic use,complications and indwelling catheter are the risk factors of urinary tract infection in patients with type 2 diabetes.

关 键 词：2型糖尿病 尿路感染 危险因素 META分析 

分 类 号：R587.1[医药卫生—内分泌] R691.3[医药卫生—内科学]