二甲双胍对心血管保护作用的研究进展  

Research progress on role of metformin in the protection of cardiovascular

作　　者：梁晓(综述) 肖丽红(审校)[2] LIANG Xiao;XIAO Li-hong(Department of General Medicine,Liuzhou Liutie Central Hospital,Liuzhou 545007,Guangxi,CHINA;Department of General Medicine,Liuzhou People's Hospital,Liuzhou 545006,Guangxi,CHINA)

机构地区：[1]柳州市柳铁中心医院全科医学科,广西柳州545007 [2]柳州市人民医院全科医学科,广西柳州545006

出　　处：《海南医学》2021年第8期1035-1039,共5页Hainan Medical Journal

基　　金：广西卫健委科研课题(编号:Z20200850)。

摘　　要：二甲双胍是一种廉价、有效的糖尿病治疗药物,已在临床前研究和临床研究中被证明能降低糖尿病患者的心血管事件。越来越多的证据表明二甲双胍除了降血糖作用外,对冠状动脉有保护作用。鉴于二甲双胍的有效性、给药途径和低成本,二甲双胍为糖尿病和非糖尿病患者的心血管保护和治疗提供了更多的选择。Metformin is a cheap and effective drug for the treatment of diabetes.It has been proved that metformin can reduce cardiovascular events in patients with diabetes mellitus in preclinical and clinical studies.More and more evidence show that metformin has a protective effect on coronary artery besides hypoglycemic effect.In view of the effectiveness,route of administration and low cost of metformin,metformin provides more choices for cardiovascular protection and treatment in diabetic and non-diabetic patients.

关 键 词：二甲双胍 心血管保护 糖尿病 冠心病 动脉粥样硬化 

分 类 号：R54[医药卫生—心血管疾病]