银屑病患者的认知障碍  

Cognitive Impairment in Psoriasis

作　　者：金利平 朱武[1] JIN Liping;ZHU Wu(Department of Dermatology,Xiangya Hospital,Central South University,Changsha 410008,China)

机构地区：[1]中南大学湘雅医院皮肤科,长沙湖南410008

出　　处：《皮肤科学通报》2021年第2期113-117,M0003,共6页Dermatology Bulletin

基　　金：国家自然科学基金(81974479,81773329)。

摘　　要：银屑病和认知障碍都是多因素致病的慢性疾病,它们具有共同的遗传因素和炎症途径,这使得人们认为这两种疾病之间可能存在联系。大多数观察性研究显示银屑病患者患轻度认知障碍或痴呆的风险增加,另有研究却显示银屑病患者与轻度认知障碍或痴呆之间为负相关。本综述系统地回顾了银屑病和认知障碍的相关研究,并强调认知筛查可以用于有认知损害主诉的银屑病患者,皮肤科医生应该更加关注银屑病患者的神经精神共病。Psoriasis and cognitive impairment are chronic diseases with multifactorial pathogenesis.They share common genetic factors and inflammatory pathways,which make people think that there may be a link between the two diseases.Most observational studies found an increased risk of mild cognitive impairment or dementia in psoriasis,while other evidence have shown a negative correlation between psoriasis and mild cognitive impairment or dementia.This review systematically reviews the related researches on psoriasis and cognitive impairment,and emphasize that cognitive screening can be considered for patients with psoriasis who present with cognitive complaints.Dermatologists should pay more attention to the neuropsychiatric comorbidities of psoriasis.

关 键 词：银屑病 认知 认知障碍 痴呆 认知筛查 

分 类 号：R758.3[医药卫生—皮肤病学与性病学]