利尿剂的种类及其在心力衰竭治疗中的研究进展  

Classification of Diuretics and Its Research Progress in the Treatment of Heart Failure

作　　者：张佳雨 汪宇 王林琳 冯六六[1] 刘新兵[1] ZHANG Jiayu;WANG Yu;WANG Linlin;FENG Liuliu;LIU Xinbing(Department of Cardiology,Shidong Hospital,Yangpu District,Shanghai,Shanghai 200438,China;Department of Critical Care Medicine,Shidong Hospital,Yangpu District,Shanghai,Shanghai 200438,China)

机构地区：[1]上海市杨浦区市东医院心内科,200438 [2]上海市杨浦区市东医院重症医学科,200438

出　　处：《实用心脑肺血管病杂志》2021年第5期8-13,22,共7页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：杨浦区重点学科建设(YP19ZA09)。

摘　　要：心力衰竭是各种心脏疾病进展的终末阶段,容量超负荷是其病理生理学的核心。利尿剂是缓解心力衰竭患者临床症状的主要药物,因此了解利尿剂的药理作用机制有助于规范利尿剂的临床应用及管理。与其他心力衰竭治疗药物相比,利尿剂的相关临床研究仍较匮乏。近年来关于利尿剂临床应用的研究受到了更多关注,本文就利尿剂的分类及其在心力衰竭治疗中的应用进展进行综述,以期为其在临床中的应用提供参考依据。Heart failure is the final stage of the progression of various heart diseases,and volume overload is the core pathophysiology.Diuretics are the main drugs to relieve clinical symptoms of patients with heart failure.Therefore,mastering the pharmacological mechanism of diuretics can help standardize the clinical application and management of diuretics.Compared with the other drugs for the treatment of heart failure,clinical studies on diuretics are still lacking.In recent years,researches on the clinical application of diuretics have received more attention.This article reviews classification of diuretics and their application in the treatment of heart failure,in order to provide reference basis for its clinical application.

关 键 词：心力衰竭 利尿剂 容量超负荷 

分 类 号：R541.61[医药卫生—心血管疾病]