双水平无创呼吸机治疗肺源性心脏病合并阻塞性睡眠呼吸暂停综合征的效果分析  

Analysis of the effect of bi-level non-invasive ventilator in the treatment of pulmonary heart disease with obstructive sleep apnea syndrome

作　　者：路婷 LU Ting(Lanzhou First People’s Hospital,Lanzhou 730050,China)

机构地区：[1]兰州第一人民医院,730050

出　　处：《中国实用医药》2021年第11期42-44,共3页China Practical Medicine

摘　　要：目的观察双水平无创呼吸机治疗肺源性心脏病(pHD)合并阻塞性睡眠呼吸暂停综合征的临床疗效。方法 60例肺源性心脏病合并阻塞性睡眠呼吸暂停综合征患者,按随机数字表法分为治疗组和对照组,各30例。对照组给予药物、运动、饮食、健康指导等常规治疗,治疗组在对照组基础上给予双水平无创呼吸机治疗。比较两组患者临床疗效、治疗前后血气分析指标及症状改善时间。结果治疗组总有效率为90.00%,高于对照组的63.33%,差异具有统计学意义(P<0.05)。治疗前,两组酸碱度(pH)值、动脉血氧分压(PaO2)、血氧饱和度(SaO2)比较差异无统计学意义(P>0.05);治疗后,治疗组pH值、PaO2、SaO2分别为(7.28±0.06)、(72.41±9.82)mm Hg(1 mm Hg=0.133 kPa)、(90.82±6.98)%,均优于对照组的(7.32±0.06)、(63.35±10.26)mm Hg、(86.24±6.44)%,差异具有统计学意义(P<0.05)。治疗组胸闷、心悸、剧烈咳嗽及呼吸困难消失时间均短于对照组,差异具有统计学意义(P<0.05)。结论双水平无创呼吸机治疗肺源性心脏病合并阻塞性睡眠呼吸暂停综合征的临床效果显著,患者的临床症状得到明显改善,且改善时间较短,完全值得被推广。Objective To observe the clinical efficacy of bi-level non-invasive ventilator in the treatment of pulmonary heart disease with obstructive sleep apnea syndrome.Methods A total of 60 cases of pulmonary heart disease(PHD)with obstructive sleep apnea syndrome were divided into treatment group and control group according to random numerical table,with 30 cases in each group.The control group was treated with conventional therapy of drugs,exercise,diet and health guidance,and the treatment group was treated with bi-level non-invasive ventilator on the basis of the control group.The clinical efficacy,blood gas analysis index before and after treatment,and symptom improvement time were compared between the two groups.Results The total effective rate of the treatment group was 90.00%,which was higher than 63.33%of the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in pH value,arterial partial pressure of oxygen(PaO2)and blood oxygen saturation(SaO2)between the two groups(P>0.05);after treatment,the pH value,PaO2 and SaO2 of the treatment group were(7.28±0.06),(72.41±9.82)mm Hg(1 mm Hg=0.133 kPa)and(90.82±6.98)%,respectively,which were all better than(7.32±0.06),(63.35±10.26)mm Hg and(86.24±6.44)%of the control group,and the difference was statistically significant(P<0.05).The disappearance time of chest tightness,palpitation,severe cough and dyspnea of the treatment group were shorter than those of the control group,and the difference was statistically significant(P<0.05).Conclusion Bi-level non-invasive ventilator shows remarkable clinical effect in the treatment of pulmonary heart disease with obstructive sleep apnea syndrome,and the improvement time is shorter.It is worthy of promotion.

关 键 词：双水平无创呼吸机 肺源性心脏病 阻塞性睡眠呼吸暂停综合征 治疗效果 

分 类 号：R541.5[医药卫生—心血管疾病] R766[医药卫生—内科学]