中性粒细胞与淋巴细胞比率在脑出血中的研究进展  

Progress in the Study of the Ratio of Neutrophils to Lymphocytes in Cerebral Hemorrhage

作　　者：刘志恒 刘劲睿[1] Liu Zhengheng;Liu Jinrui(The First Affiliated Hospital of Jiamusi University,Jiamusi 154000,China)

机构地区：[1]佳木斯大学附属第一医院,黑龙江佳木斯154000

出　　处：《广东化工》2021年第4期115-116,114,共3页Guangdong Chemical Industry

摘　　要：自发性脑出血约占所有急性脑血管事件的10%至30%,免疫反应早期由血肿成分触发,可增加脑内损伤。评估炎症的外周生物标志物有助于增加对ICH所致损伤机制的了解,并提供有关疾病的生理病理过程的信息。本综述的目的是突出现有的证据,说明免疫反应的相关病理生理机制,以及中性粒细胞/淋巴细胞比率与急性ICH患者临床结果之间的关系,期望为确定神经保护的新的潜在靶点,并制定新的治疗策略提供新思路。Spontaneous intracerebral haemorrhage accounts for about 10%to 30%of all acute cerebrovascular events,and an early immune response triggered by hematoma components can increase brain damage.Evaluation of peripheral biomarkers of inflammation helps to increase understanding of the mechanisms of ICH-induced injury and provides information on the physiological and pathological processes of the disease.The purpose of this review is to provide evidence on the pathophysiology of immune responses and the relationship between neutrophil/lymphocyte ratios and clinical outcomes in patients with acute ICH,and to provide new insights into new potential targets for neuroprotection and new treatment strategies.

关 键 词：脑出血 中性粒细胞 免疫反应 

分 类 号：TQ[化学工程]