妊娠期糖尿病复发的危险因素分析  

Risk factors analysis of recurrence of Gestational Diabetes Mellitus in pregnant women

作　　者：章洁[1] 杨春[1] 韩云[2] 周文燕 时惠霞[1] ZHANG Jie;YANG Chun;HAN Yun;ZHOU Wenyan;SHI Huixia(Department of Obstetrics,Changzhou No.2 People's Hospital,Nanjing Medical University,Changzhou,213000,China)

机构地区：[1]南京医科大学附属常州市第二人民医院产科,江苏省常州市213000 [2]南京医科大学附属常州市第二人民医院内分泌科,江苏省常州市213000

出　　处：《中国护理管理》2021年第4期498-502,共5页Chinese Nursing Management

基　　金：南京医科大学康达学院科研发展基金(KD2017KYJJYB023)。

摘　　要：目的:分析妊娠期糖尿病(GDM)患者再妊娠时该病复发的危险因素。方法:选取2010年1月至2020年3月,既往确诊GDM且再次妊娠时在本院产检分娩的孕妇269例,其中再次诊断GDM的132例孕妇作为复发组,其余137例作为对照组,采用Logistic回归模型筛选GDM复发的危险因素,受试者工作特征(ROC)曲线分析其预测价值。结果:再次妊娠时GDM复发率高达49.1%,Logistic回归显示初次妊娠时的新生儿体质量和两次妊娠间的体质量变化是GDM复发的独立危险因素(P<0.001)。ROC曲线提示初次妊娠时新生儿体质量和孕妇两次妊娠间体质量变化预测GDM再发的曲线下面积(AUC)分别为0.684和0.702,两者联合时为0.760。结论:GDM复发率较高,早期识别高危人群进行针对性的护理干预,是降低复发风险、提高妊娠质量的有效措施。Objective:To explore risk factors which can predict the recurrence of Gestational Diabetes Mellitus(GDM).Methods:We evaluated women who experienced GDM in the previous pregnancy and had the subsequent pregnancy in our hospital between January 2010 and March 2020.A total of 269 women were finally included,132 women with recurrent GDM were enrolled into the experiment group,while 137 women without recurrent GDM as the control group.Logistic regression analysis was performed to identify the independent risk factors of recurrent GDM and the Receiver Operating Characteristic(ROC)curve was applied to evaluate the predictive values.Results:The frequency of recurrent GDM in subsequent pregnancies was 49.1%.Logistic regression revealed that both neonatal birthweight in the index pregnancy and weight change between pregnancies were independent predictors of recurrent GDM(P<0.001).Moreover,the Area Under the Curve(AUC)of neonatal birthweight in the index pregnancy and weight change between pregnancies for predicting recurrent GDM were 0.684 and 0.702 respectively,the AUC of these two combined factors was 0.760.Conclusion:GDM is a common complication with high recurrence,targeted nursing interventions should be carried out to reduce recurrence risks and improve the pregnancy outcomes.

关 键 词：妊娠期糖尿病 复发 危险因素 再妊娠 

分 类 号：R47[医药卫生—护理学]