锝-99m定量SPECT/CT临床应用进展  

Progress in Clinical Applications of Technetium-99m Quantitative SPECT/CT

作　　者：龚成鹏 李坤[1] 胡佳[1] 高再荣[1] Gong Chengpeng;Li Kun;Hu Jia(Department of Nuclear Medicine,Union Hospital,Tongji Medical College,Huazhong University of Scienceand Technology,Hubei Key Laboratory of Molecular Imaging,Wuhan 430022,China)

机构地区：[1]华中科技大学同济医学院附属协和医院核医学科,分子影像湖北省重点实验室,武汉430022

出　　处：《华中科技大学学报（医学版）》2021年第2期247-250,265,共5页Acta Medicinae Universitatis Scientiae et Technologiae Huazhong

基　　金：华中科技大学自主创新研究基金项目(No.2017KFYXJJ231)。

摘　　要：SPECT/CT融合技术、图像重建算法、光子补偿技术等的不断完善和应用使得单光子发射计算机断层扫描(single photon-emission computed tomography,SPECT)已经能够开展类似于正电子发射型计算机断层扫描(positron-emission tomography,PET)的定量分析。SPECT/CT定量分析中使用最多的是锝-99m(technetinum-99m,99mTc)标记的放射性药物,该文综述了99mTc定量SPECT/CT在骨关节、甲状腺等疾病中的应用及局限,并对定量SPECT/CT的应用前景进行了展望。With the development and application of SPECT/CT fusion technology,image reconstruction algorithm and photon compensation technology,the single-photon emission computed tomography(SPECT)has been able to conduct quantitative analysis similar to positron-emission computed tomography(PET).Technetium-99 m(99 mTc)labelled radiopharmaceuticals are most commonly used in SPECT/CT quantitative analysis.This article reviews the application and limitation of 99 mTc quantitative SPECT/CT in bone,joint and thyroid diseases,and prospects the application of 99 mTc quantitative SPECT/CT.

关 键 词：SPECT/CT 定量分析 锝-99m 临床应用 

分 类 号：R817[医药卫生—影像医学与核医学]