茶叶儿茶素的癌症化学预防增效机制研究进展  

Advances in Synergistic Mechanism of Tea Catechins on Cancer Chemoprevention

作　　者：乔小燕 陈栋[1,2,3] 刘仲华[1,2] QIAO Xiaoyan;CHEN Dong;LIU Zhonghua(Key Laboratory of Tea Science of Ministry of Education,Hunan Agricultural University,Changsha 410128,China;National Research Center of Engineering Technologies for Utilization of Functional Ingredients from Botanicals,Hunan Agricultural University,Changsha 410128,China;Tea Research Institute,Guangdong Academy of Agricultural Science,Guangzhou 510640,China)

机构地区：[1]湖南农业大学茶学教育部重点实验室,湖南长沙410128 [2]国家植物功能成分利用工程技术研究中心,湖南农业大学,湖南长沙410128 [3]广东省农业科学院茶叶研究所,广东广州510640

出　　处：《食品与生物技术学报》2021年第2期1-9,共9页Journal of Food Science and Biotechnology

基　　金：国家茶叶产业技术体系项目(CARS1909B);广东省农村科技领域项目(2017A020208020)。

摘　　要：研究证实,茶叶中儿茶素对预防癌症起到重要的作用,其中表没食子儿茶素没食子酸酯(EGCG)具有比较强的抗氧化、抑制癌细胞增殖和诱导细胞的凋亡能力,是化学预防癌症最具潜力的天然产物之一。作者归纳了儿茶素的生物活性、EGCG与天然抗癌产物和临床药物的增效机制研究进展,为更加深入地开展EGCG癌症化学预防机制研究提供参考。Experiments have confirmed that tea is effective in preventing cancer,and catechins play the important role,among which EGCG has strong anti-oxidation to inhibit cancer cell proliferation and induce cancer cell apoptosis.EGCG is also one of the most potential natural products for cancer chemoprevention.In this paper,the biological activities of catechins were reviewed.Synergistic mechanism of EGCG with natural anticancer products and clinical reagents was summarized,to provide a reference for further research on cancer chemoprevention mechanism.

关 键 词：茶 EGCG 化学预防 增效 

分 类 号：S571[农业科学—作物学]