高频超声联合磁敏感成像诊断早产儿脑损伤的临床价值  

Clinical value of high frequency ultrasound combined with magnetic sensitive imaging in the diagnosis of brain injury in preterm infants

作　　者：丁小军[1] 杨宏[1] 周翠翠[1] 许松[1] 黄志平[1] 林霖[1] DING Xiao-jun;YANG Hong;ZHOU Cui-cui;XU Song;HUANG Zhi-ping;LIN Lin(Department of Ultrasound,Ganzhou People's Hospital,Jiangxi Province,Ganzhou341000,China)

机构地区：[1]江西省赣州市人民医院超声科,江西赣州341000

出　　处：《中国当代医药》2021年第13期152-155,共4页China Modern Medicine

基　　金：江西省赣州市指导性科技计划任务(GZ2018ZSF 134)。

摘　　要：目的探讨高频超声联合磁敏感成像(SWI)诊断早产儿脑损伤的临床价值。方法选取2018年8月~2020年2月于赣州市人民医院分娩的存在脑损伤高危因素的60例早产儿作为研究对象,所有早产儿同时行高频超声和SWI检查,比较单独高频超声检查、单独SWI检查和高频超声联合SWI检查的阳性检出率以及特异度、敏感度和准确性,并分析各类早产儿脑损伤SWI的影像学表现。结果高频超声联合SWI检查组早产儿脑损伤阳性检出病率为97.50%,高于单独高频超声组(52.50%)和单独SWI组(77.50%),差异有统计学意义(P<0.05)。高频超声联合SWI检查的特异度、敏感度和准确性均高于单独高频超声和单独SWI,差异有统计学意义(P<0.05)。脑白质损伤的早产儿SWI检查可见点状或斑片状低信号;颅内出血早产儿出血灶在SWI上多呈低信号;脑水肿患儿SWI均检测到不同程度的高信号改变。结论高频超声适用于对早期病情不稳定的早产儿进行床旁动态监测,高频超声联合SWI对早产儿脑损伤的诊断阳性率较高,值得临床推广。Objective To explore the clinical value of high-frequency ultrasound combined with magnetic sensitivity imaging(SWI)in the diagnosis of preterm infants with brain injury.Methods A total of 60 premature infants with high risk factors for brain injury who were delivered in Ganzhou People′s Hospital from August 2018 to February 2020 were selected as the research subjects,all preterm infants were examined by high-frequency ultrasound and SWI simultaneously.The positive detection rates,specificity,sensitivity and accuracy of high-frequency ultrasound alone,SWI alone and high-frequency ultrasound combined with SWI were compared,and the imaging findings of SWI in premature infants with brain injury were analyzed.Results The positive rate of preterm brain injury in the high-frequency ultrasound combined with SWI group was 97.50%,which was higher than that in the high-frequency ultrasound group alone(52.50%)and SWI group alone(77.50%),and the differences were statistically significant(P<0.05).The specificity,sensitivity and accuracy of high-frequency ultrasound combined with SWI were higher than those of high-frequency ultrasound alone and SWI alone,and the differences were statistically significant(P<0.05).SWI examination of premature infants with white matter injury showed spotty or patchy low signal.The hemorrhage foci of premature infants with intracranial hemorrhage showed low signal on SWI.The SWI of the children with cerebral edema showed different degree of high signal change.Conclusion High-frequency ultrasound is suitable for bedside dynamic monitoring of premature infants with unstable early stage.High-frequency ultrasound combined with SWI has a high diagnostic positive rate for brain injury in preterm infants,which is worthy of clinical promotion.

关 键 词：高频超声 磁敏感成像 早产儿 脑损伤 临床价值 

分 类 号：R722.6[医药卫生—儿科]