Mediation role of cardiorespiratory fitness on the association between fatness and cardiometabolic risk in European adolescents: The HELENA study  

作　　者：Carlos Cristi-Montero Javier Courel-Ibanez Francisco B.Ortega Jose Castro-Pinero Alba Santaliestra-Pasias Angela Polito Jeremy Vanhelst Ascension Marcos Luis M.Moreno Jonatan R.Ruiz 

机构地区：[1]IRyS Group,Physical Education School,Pontificia Universidad Catolicade Valparaiso,Valparaisso 2530388,Chile [2]Department of Physical Activity and Sport,Faculty of Sport Sciences,University of Murcia,Murcia 30071,Spain [3]PROmoting FITness and Health through Physical Activity Research Group(PROFITH),Department of Physical Education and Sports,Faculty of Sport Sciences,University of Granada,Granada 18001,Spain [4]Department of Physical Education,Faculty of Education Sciences,University of Cadiz,Puerto Real 11003,Spain [5]Department of Health and Human Performance,School of Health Sciences,University of Zaragoza,Zaragoza 50001,Spain [6]Growth,Exercise,Nutrition and Development(GENUD)Research Group,Zaragoza 50001,Spain [7]National Institute for Food and Nutrition Research,Rome 80070,Italy [8]Lille Inflammation Research International Center,University of Lille,Lille 59000,France [9]Immunonutrition Research Group,Department Metabolism and Nutrition,Institute of Food Science and Technology and Nutrition(ICTAN),Spanish National Research Council(CSIC),Madrid E-28040 Spain

出　　处：《Journal of Sport and Health Science》2021年第3期360-367,共8页运动与健康科学（英文）

摘　　要：Purpose:This study was aimed to analyze the mediation role of cardiorespiratory fitness(CRF)on the association between fatness and cardiometabolic risk scores(CMRs)in European adolescents.Methods:A cross-sectional study was conducted in adolescents(n=525;46%boys;14.1±1.1 years old,mean ±SD)from 10 European cities involved in the Healthy Lifestyle in Europe by Nutrition in Adolescence study.CRF was measured by means of the shuttle run test,while fatness measures included body mass index(BMI),waist to height ratio,and fat mass index estimated from skinfold thicknesses.A clustered CMRs was computed by summing the standardized values of homeostasis model assessment,systolic blood pressure,triglycerides,total cholesterol/highdensity lipoprotein cholesterol ratio,and leptin.Results:Linear regression models indicated that CRF acted as an important and partial mediator in the association between fatness and CMRs in 1217-year-old adolescents(for BMI:coefficients of the indirect role b=0.058(95%confidence interval(95%CI):0.023-0.101),Sobel test z=3.11(10.0%mediation);for waist to height ratio:b=4.279(95%CI:2.242-7.059),z=3.86(11.5%mediation);and for fat mass index:b=0.060(95%CI:0.020-0.106),z=2.85(9.4%mediation);all p<0.01).Conclusion:In adolescents,the association between fatness and CMRs could be partially decreased with improvements to fitness levels;therefore,CRF contribution both in the clinical field and public health could be important to consider and promote in adolescents independently of their fatness levels.

关 键 词：Cardiovascular disease Children Fat mass FITNESS HEALTH Physical activity 

分 类 号：G804.2[文化科学—运动人体科学]