高通量测序在种群遗传学中的分析方法  

Analysis Methods of High-Fluxed DNA Sequencing Technology in Population Genetics

作　　者：任月 王政昆 朱万龙 Ren Yue;Wang Zhengkun;Zhu Wanlong(Key Laboratory of Ecological Adaptive Evolution and Conservation on Animals-Plants in Southwest Mountain Ecosystem of Yunnan Province Higher Institutes College,School of Life Sciences,Yunnan Normal University,Key Laboratory of Biomass Energy and Environmental Biotechnology in Yunnan Province,Engineering Research Center of Sustainable Development and Utilization of Biomass Energy Ministry of Education,Kunming,Yunnan 650500,China)

机构地区：[1]云南省高校西南山地生态系统动植物生态适应进化及保护重点实验室,云南师范大学生命科学学院,生物能源持续开发利用教育部工程研究中心,云南省生物质能与环境生物技术重点实验室,云南昆明650500

出　　处：《绿色科技》2021年第8期1-3,共3页Journal of Green Science and Technology

基　　金：云南师范大学研究生核心课程建设项目(编号:YH2018-B10)。

摘　　要：随着基因组测序技术的不断发展,越来越多人研究人类和不同种群基因组。综述了高通量测序在种群基因组学中的分析方法,包括获取多态性位点、基因组自然选择的检测方法、种群遗传分析方法、种群历史动态的重建和研究方法。以期为种群遗传进化的研究和实践提供一些方法。With the continuous development of genome sequencing technology,more and more people are studying human and different species genome.The paper introduces the analysis methods of high-fluxed DNA sequencing technology in population genomics,including the methods of acquisition of polymorphic sites,detection of genomic natural selection,population genetic analysis,reconstruction of population historical dynamics and research methods,which provides some methods for research and practice of population genetic evolution.

关 键 词：SNP 种群结构 PSMC 高通量测序 

分 类 号：Q347[生物学—遗传学]