厚皮香地上部分化学成分研究  

Chemical Constituents of Aerial Parts of Ternstroemia gymnanthera

作　　者：刘明 李骅轩 沈怡 肖朝江 姜北 Liu Ming;Li Huaxuan;Shen Yi;Xiao Chaojiang;Jiang Bei(Institute of Materia Medica,Dali University,Dali,Yunnan 671000,China;College of Pharmacy,Dali University,Dali,Yunnan 671000,China)

机构地区：[1]大理大学药物研究所,云南大理671000 [2]大理大学药学院,云南大理671000

出　　处：《大理大学学报》2021年第4期1-3,共3页Journal of Dali University

基　　金：国家自然科学基金项目(81641187)。

摘　　要：目的:研究厚皮香地上部分的化学成分。方法:采用硅胶和Sephadex LH-20等柱色谱对厚皮香化学成分进行分离纯化,并通过理化性质及现代波谱分析等手段对化合物进行结构鉴定。结果:从厚皮香地上部分95%乙醇提取物的乙酸乙酯部位分离鉴定出5个化合物,分别为白桦酸(1)、3-表熊果酸(2)、熊果酮酸(3)、α-菠甾醇-β-D-吡喃葡萄糖苷(4)、3,4-二羟基苯乙酸丁酯(5)。结论:化合物2、3、5为首次从厚皮香属植物中分离得到。Objective:To study the chemical constituents of aerial parts of Ternstroemia gymnanthera(wight et Arn.)Beddome.Methods:The chemical constituents of T.gymnanthera were isolated and purified by column chromatography padded with silica gel and Sephadex LH-20.The structures of the compounds were identified based on the comprehensive analyses of the physicochemical properties and modern spectral analysis techniques.Results:Five compounds were obtained from ethyl acetate part of 95%ethanol extract of aerial parts of T.gymnanthera and identified as betulinic acid(1),3-epiursolic acid(2),ursonic acid(3),α-spinasterol-β-D-glucopyranoside(4),and butyl-2-(3,4-dihydroxyphenyl)acetate(5).Conclusion:Compounds 2,3 and 5 were isolated from the genus Ternstroemia for the first time.

关 键 词：厚皮香 地上部分 化学成分 三萜 

分 类 号：R284.1[医药卫生—中药学]