妊娠糖尿病患者治疗中采用胰岛素泵短期强化疗法的效果  

Effect of Short-term Intensive Insulin Pump Therapy in the Treatment of Gestational Diabetes Mellitus

作　　者：李婷婷 韩瑞[1] 林杨[1] LI Ting-ting;HAN Rui;LIN Yang(Department of Endocrinology,First Hospital of Qiqihar City,Qiqihar,Heilongjiang 161000)

机构地区：[1]齐齐哈尔市第一医院内分泌一科,黑龙江齐齐哈尔161000

出　　处：《智慧健康》2021年第1期108-110,共3页Smart Healthcare

摘　　要：目的研究胰岛素泵短期强化治疗妊娠糖尿病(Gestational diabetes mellitus,GDM)患者的临床效果。方法选取2018年12月至2019年12月期间本院收治的86例GDM患者作为研究对象,随机分为对照组(43例)和观察组(43例);86例患者均接受营养支持、健康宣教、心理维护等综合治疗干预措施,在此基础上对照组采取皮下注射胰岛素治疗,对观察组予以胰岛素泵短期强化疗法;对比两组患者血糖控制情况,以及母婴并发症情况。结果治疗前,两组患者血糖水平接近,t1=0.1248,t2=0.1161,P1=0.9010,P2=0.9078,差异无统计学意义;治疗后,观察组空腹血糖(Fasting blood glucose,FBG)为(5.16±0.38)mmol/L、餐后2h血糖(Postprandial Blood Glucose,PBG)(6.24±0.98)mmol/L,均明显低于对照组(6.34±0.72) mmol/L、(7.03±1.27) mmol/L,t3=9.5044,t4=3.2293,P3=0.0000,P4=0.0018,差异有统计学意义;并发症方面,观察组总发生率(39.54%)明显低于对照组(69.77%),c2=7.9291,P=0.0048,有统计学意义。结论经过胰岛素泵短期强化治疗,GDM患者的血糖控制效果及母婴并发症情况均较为理想,具备临床推广价值。Objective To study the clinical effect of short-term intensive treatment with insulin pump in patients with gestational diabetes mellitus (GDM).Methods 86 cases of GDM patients in our hospital from December 2018 to December 2019 were selected and randomly divided into control group (43 cases) and observation group (43 cases).86 cases of patients received comprehensive treatment and intervention measures such as nutritional support,health education,psychological maintenance,etc.on this basis,the control group was treated with continuous subcutaneous insulin injection,and the observation group was given short-term intensive insulin pump therapy Methods:compared the two groups of patients with blood glucose control,as well as maternal and infant complications.Results Before treatment,the blood glucose levels of the two groups were similar,t1=0.1248,t2=0.1161,P1=0.9010,P2=0.9078.After treatment,fasting blood glucose (FBG) and postprandial blood glucose (PBG) (6.24±0.98) mmol/L in the observation group were significantly lower than those in the control group (6.34±0.72) mmol/L,(7.03±1.27) mmol/L,t3=9.5044,t4=3.2293,P3=0.0000,P4=0.0018,the difference was statistically significant.The total incidence of complications in the observation group (39.54%) was significantly lower than that in the control group (69.77%),c2=7.9291,P=0.0048,with statistical significance.Conclusion After short-term intensive treatment with insulin pump,the blood glucose control effect and maternal and infant complications of GDM patients are ideal,which has the clinical promotion value.

关 键 词：妊娠并发症 妊娠糖尿病 胰岛素 皮下注射 胰岛素泵 短期强化治疗 血糖 新生儿并发症 

分 类 号：R714.256[医药卫生—妇产科学]