肥胖对男性生殖的影响研究进展  

Advance in the influence of obesity on male reproduction

作　　者：张爱萍[1] 郝永璐 王燕超[1] 马鹏程[1] 王一青[1] Zhang Aiping;Hao Yonglu;Wang Yanchao;Ma Pengcheng;Wang Yiqing(The Assisted Reproductive Medicine Center of The First Hospital of Lanzhou University,Key Laboratory for Reproductive Medicine and Embryo of Gansu Province)

机构地区：[1]兰州大学第一医院生殖医学专科医院、甘肃省生殖医学与胚胎重点实验室,兰州730000

出　　处：《重庆医科大学学报》2021年第4期439-443,共5页Journal of Chongqing Medical University

基　　金：国家自然科学基金资助项目(编号:81960624)。

摘　　要：由于生活习惯和饮食结构改变,全球肥胖人口逐渐增多,发展中国家肥胖人群比率也大幅增加。肥胖者能量摄取和消耗失衡,脂肪积累过度,干扰人体正常代谢,引起心血管疾病和代谢综合征,还影响男性生殖内分泌调节,引起全身和局部的炎症反应以及过度的氧化应激和凋亡,损害精子生成及成熟的内环境,造成男性的性功能障碍,精子质量下降,生育能力降低。Due to the changes of living habits and diet structure,the number of obese people in the world is increasing gradually,and the proportion of obese people in developing countries is also increasing greatly.Obese people have unbalanced energy intake,excessive obesity accumulation,interfering the normal metabolism of human body,and causing cardiovascular diseases and metabolic syndrome.And the obesity can cause systemic and local inflammatory response,excessive oxidative stress and apoptosis,and damage the internal environment of spermatogenesis and maturation by affecting male reproductive endocrine regulation,resulting in male sexual dysfunction,decreased sperm quality and fertility.

关 键 词：肥胖 男性 生殖 

分 类 号：R698.2[医药卫生—泌尿科学]