今非昔比:重视复治肺结核的合理施治  

Pay attention to the reasonable treatment of retreatment tuberculosis:today is not what it used to be

作　　者：马艳[1] 高微微[2] MA Yan;GAO Wei-wei(Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China;不详)

机构地区：[1]中国中医科学院中医临床基础医学基础所,北京100700 [2]首都医科大学附属北京胸科医院,北京市结核病胸部肿瘤研究所,中国疾病预防控制中心结核病防治临床中心

出　　处：《中国防痨杂志》2021年第4期313-317,共5页Chinese Journal of Antituberculosis

基　　金：“十三五”国家科技重大专项(2018ZX10722302-003);“十二五”国家科技重大专项(2013ZX10003009-001-006、2013ZX10003009-001-007、2013ZX10003009-001-008、2013ZX10003009-001-009);“十一五”国家科技重大专项(2008ZX10003-015-2)。

摘　　要：及时合理的抗结核治疗是有效治愈结核病患者、消除传染性和阻断疾病传播的关键措施。复治标准化治疗方案的实施曾对提高复治肺结核患者治疗成功率起到显著效果。但结核分枝杆菌在不断演变和进化,患者的个体情况也在不断变化,加之当前抗结核药物治疗效果欠佳的现状,原来的复治标准化治疗方案应考虑进行相应调整及更新。笔者就目前复治肺结核治疗对象、治疗方案演变及其合理应用等结合文献和临床经验进行论述。Timely and reasonable anti-tuberculosis treatment is a key measure to effectively cure tuberculosis patients,eliminate infectivity and stop the spread of the disease.The implementation of standardized retreatment regimens has played a significant role in improving the success rate of retreatment pulmonary tuberculosis patients.But Mycobacterium tuberculosis is constantly evolving,and the individual conditions of patients are also constantly changing.In addition to the current status of poor anti-tuberculosis drug treatment,the standardized retreatment regimens should be adjusted and updated accordingly.In this article,the target of retreatment pulmonary tuberculosis,the evolution of the retreatment regimens and its rational application will be discussed by the author in combination with literature and clinical experience.

关 键 词：结核 再治疗 药物疗法 联合 方案评价 

分 类 号：R521[医药卫生—内科学]