应用于人体环境的长周期光纤光栅葡萄糖传感器  

Glucose sensor based on long period fiber grating for human environment

作　　者：沈迪[1] 孙晓岚[1] 严钰杨 范美端 周爽 SHEN Di;SUN Xiaolan;YAN Yuyang;FAN Meiduan;ZHOU Shuang(Key Laboratory of Specialty Fiber Optics and Optical Access Networks,Shanghai University,Shanghai 200444,China)

机构地区：[1]上海大学特种光纤与光接入网重点实验室,上海200444

出　　处：《光通信技术》2021年第5期36-39,共4页Optical Communication Technology

基　　金：2019年度“科技创新行动计划”政府间国际合作项目(课题编号:19530714000)资助。

摘　　要：为了提高葡萄糖传感器在人体环境(pH值为7.4)的检测灵敏度,提出了一种基于苯硼酸衍生物的长周期光纤光栅葡萄糖传感器,传感器将四乙烯基苯硼酸通过C=C双键重组的方式聚合在长周期光纤光栅表面,用于测量葡萄糖浓度。实验结果表明:该葡萄糖传感器在多次使用后中心波长仍可复位原点,在葡萄糖溶液pH值为7.4、浓度为0.1~3 mg/mL范围内的灵敏度为0.34 nm/(mg·mL^(-1))。此外,该传感器在反复测定和长时间阶段测定仍然保持良好的一致性和稳定性。In order to improve the detection sensitivity of glucose sensor in human environment(pH=7.4),a long period grating glucose sensor based on phenylboronic acid derivative is proposed.4-vinylphenylboronic acid is polymerized on the surface of long period grating by C=C double bond recombination to measure glucose concentration.The experimental results show that the central wavelength of the glucose sensor can be reset to the original point after multiple repeated use,the sensitivity of the glucose sensor is 0.34 nm/(mg·mL^(-1))in the range of pH=7.4 and concentration of 0.1~3 mg/mL.Besides,the results show that the glucose sensor has good consistency and stability in repeated and long-term glucose determination.

关 键 词：葡萄糖传感器 人体环境 长周期光纤光栅 苯硼酸 四乙烯基苯硼酸 

分 类 号：TN256[电子电信—物理电子学]