OCT血管成像技术在糖尿病性黄斑水肿中的应用研究  

Application of OCT Angiography in Diabetic Macular Edema

作　　者：李胜[1] 刘丁熙[1] 纪莉莉[1] 祁媛媛[1] LI Sheng;LIU Dingxi;JI Lili;QI Yuanyuan(The Third People’s Hospital of Dalian,Dalian 116033,China;不详)

机构地区：[1]辽宁省大连市第三人民医院,辽宁大连116033

出　　处：《中国医学创新》2021年第12期39-43,共5页Medical Innovation of China

基　　金：2018年大连市医学科学研究计划项目(1811049)。

摘　　要：目的:探讨OCT血管成像技术在糖尿病性黄斑水肿中的应用价值。方法:回顾性分析本院2017年8月-2019年8月39例(52眼)疑似黄斑水肿患者的临床资料,患者均进行眼底血管造影、OCT血管成像技术检查。比较两种检查方法对于黄斑水肿分型的结果,以及OCT血管成像技术检查诊断符合率,并计算灵敏度、特异度。结果:纳入52只眼,眼底血管造影检查结果分型:弥漫水肿型20只眼(38.46%)、无渗漏型16只眼(30.77%)、局部水肿型15只眼(28.85%)、缺血型1只眼(1.92%);OCT血管成像技术检查结果分型:海绵样水肿型21只眼(40.38%)、黄斑囊样水肿16只眼(30.77%)、正常9只眼(17.31%)、中心凹浆液性脱离6只眼(11.54%)。OCT血管成像技术诊断符合率为82.69%,诊断灵敏度为97.22%,特异度为50.00%。有临床意义的黄斑水肿患者激光光凝术后视网膜厚度均低于治疗前(P<0.05)。结论:OCT血管成像技术在糖尿病性黄斑性水肿诊断、病情评估等方面均有重要的应用价值,为临床医师评估有临床意义的黄斑性水肿术后病情提供客观依据。Objective:To explore the application value of OCT angiography in diabetic macular edema.Method:The clinical data of 39 patients(52 eyes)with suspected macular edema in our hospital from August 2017 to August 2019 were retrospectively analyzed.All patients underwent fundus angiography and OCT angiography.The results of two methods for the classification of macular edema and the diagnostic coincidence rate of OCT angiography were compared,and the sensitivity and specificity were calculated.Result:52 eyes were enrolled in this study,the results of fundus angiography were classified as diffuse edema type in 20 eyes(38.46%),non-leakage type in 16 eyes(30.77%),local edema type in 15 eyes(28.85%)and ischemic type in 1 eye(1.92%).The results of OCT angiography were classified as spongiform edema type in 21 eyes(40.38%),macular cystoid edema type in 16 eyes(30.77%),normal 9 eyes(17.31%),serous detachment of the fovea occurred in 6 eyes(11.54%).The diagnostic accuracy,sensitivity and specificity of OCT angiography were 82.69%,97.22%and 50.00%,respectively.The retinal thickness of macular edema patients after laser photocoagulation were lower than those before treatment(P<0.05).Conclusion:OCT angiography has important application value in the diagnosis and evaluation of diabetic macular edema.It can provide objective basis for clinicians to evaluate the postoperative condition of clinical significance macular edema.

关 键 词：OCT血管成像技术 眼底血管造影 黄斑水肿 

分 类 号：R587.2[医药卫生—内分泌] R774.5[医药卫生—内科学]