远程缺血预适应心肌保护机制的临床进展  

Clinical progress of myocardial protection mechanism of remote ischemic preconditioning

作　　者：孙素娟 方哲 SUN Su-juan;FANG Zhe(Department of Cardiology,Yanbian University Hospital,Yanji 133000,China;Department of Cardiology,Daxing Hospital Affiliated To Capital Medical University,Beijing 102600,China)

机构地区：[1]延边大学附属医院心内科,吉林省延吉市133000 [2]首都医科大学大兴教学医院诊疗中心

出　　处：《中国心血管病研究》2021年第4期377-380,共4页Chinese Journal of Cardiovascular Research

摘　　要：急性心肌梗死的发病与缺血/再灌注引起的组织损伤有关。远程缺血预适应通过减轻心肌缺血再灌注损伤达到心肌保护作用。远程缺血预适应的心肌保护机制尚未完全清楚,大量实验研究证实存在体液假说和神经假说,并且两者之间具有协同作用。本文对近几年来远程缺血预适应心肌保护机制及临床进展作一综述。Acute myocardial infarction is related to tissue damage caused by ischemia/reperfusion.Remote ischemic preconditioning can protect myocardium by alleviating myocardial ischemia-reperfusion injury.The myocardial protection mechanism of remote ischemic preconditioning is not yet fully understood.A large number of experimental studies have confirmed the existence of humoral and neural hypothesis and there is a synergistic effect between them.This article reviews the mechanism and clinical progress of myocardial protection of remote ischemic preconditioning in recent years.

关 键 词：远程缺血预适应 急性心肌梗死 心肌缺血再灌注损伤 心肌保护机制 

分 类 号：R542.2[医药卫生—心血管疾病]