泻黄散的古代文献沿革分析  

Analysis on Evolution of Ancient Documents of Xiehuangsan

作　　者：杨翠玲 赵梦洁 赵琼[1] 周江[1] 张肖瑾 魏玉苹 YANG Cui-ling;ZHAO Meng-jie;ZHAO Qiong;ZHOU Jiang;ZHANG Xiao-jin;WEI Yu-ping(Affiliated Hospital/Clinical School of Chengdu University of Traditional Chinese Medicine(TCM),Chengdu 610075,China;Chengdu University of TCM,Chengdu 610000,China)

机构地区：[1]成都中医药大学附属医院/临床医学院,610075成都 [2]成都中医药大学,成都610000

出　　处：《中国实验方剂学杂志》2021年第9期32-39,共8页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家重点研发计划项目(2018YFC1704104);四川省教育厅科研项目(17ZB0157)。

摘　　要：泻黄散出自钱乙《小儿药证直诀》,由石膏、栀子、防风、藿香和甘草5味药物组成,用于治疗小儿脾热弄舌之证。随着后世医家临证使用,逐步扩大该方病证范围,包括口疮口臭、唇口干燥、目黄、口甘等,现代医家运用该方治疗小儿厌食、便秘、过敏性紫癜、抽动障碍等多种疾病。目前对于经典名方的研究已越来越受到重视,同时关于中药经典名方复方制剂的申报,必须要进行古籍文献研究和考证,故从古籍出发,考证方剂的源流,梳理分析文献,研究主治衍变规律、制剂、服法、禁忌等成为经典名方研究的重要内容。笔者通过检索多种中医古籍数据库,搜集中医古籍中泻黄散的相关文献相关记载,共获得相关古代文献数据242条,涉及中医古籍131种。通过对历代文献相关记载的梳理,分析和考证泻黄散的历史沿革、方剂源流及组成、主治病证、用药剂量、中药本草考证和基原确定及方剂制法服法等,详细论述泻黄散的历史变化及其内在联系,以期为泻黄散的现代开发研究提供文献参考和理论依据。Xiehuangsan,derived from QIAN Yi’s Key to Therapeutics of Children’s Diseases,consists of 5 medicines,namely Gypsum Fibrosum,Gardeniae Fructus,Saposhnikoviae Radix,Pogostemonis Herba and Glycyrrhizae Radix et Rhizoma. It is used to treat children with spleen heat and tongue scratching. With the clinical use of later generations of physicians,the scope of diseases and syndromes of this prescription was gradually expanded,including aphthous bad breath,dry lips,yellow eyes,and sweet mouth. Modern doctors used this prescription to treat children with anorexia,constipation,allergic purpura,tic disorder,and other diseases. At present,more and more attention has been paid to the research of classical famous prescriptions. At the same time,the application of classical famous prescriptions of traditional Chinese medicine(TCM)must be researched and verified in ancient literature. Therefore,it has become important contents in the study of classic prescriptions that researching the source of prescriptions from the ancient books,combing and analyzing literature,and studying the evolution rules of indications,preparations,methods of administration and taboos. The author searched a variety of ancient Chinese medicine databases and collected the relevant documents related to Xiehuangsan in ancient medical books. A total of 242 pieces of relevant ancient document data were obtained,involving 131 types of ancient Chinese medicine books. Through combing the relevant records of historical documents,this paper analyzes and researches the historical evolution of Xiehuangsan,the source and composition of the prescriptions,the indications,the dosage,the textual research of Chinese herbal medicine and the determination of the basis,and the method of prescription preparation and administration,etc. The historical changes of Xiehuangsan and its internal relations are expected to provide literature references and theoretical basis for the modern development and research of Xiehuangsan.

关 键 词：泻黄散 脾胃伏火 历史沿革 《小儿药证直诀》 

分 类 号：R284.2[医药卫生—中药学] R289[医药卫生—中医学]