牙周炎与心血管疾病联系机制的研究  

Study on the Link Mechanism Between Periodontitis and Cardiovascular Disease

作　　者：左楠 刘文辉 李伟[1] 于洋[1] 胡腾龙[1] ZUO Nan;LIU Wen-hui;LI Wei;YU Yang;HU Teng-long(Department of Oral and Maxillofacial Surgery,the First Affiliated Hospital of Harbin Medical University,Harbin 150001,Heilongjiang,China)

机构地区：[1]哈尔滨医科大学附属第一医院口腔颌面外科,黑龙江哈尔滨150001

出　　处：《医学信息》2021年第10期50-53,共4页Journal of Medical Information

基　　金：哈尔滨医科大学附属第一医院科研创新基金项目(编号:2020M12)。

摘　　要：牙周炎作为一种慢性进行性炎症性疾病,一定程度上影响着全身系统的健康。大量统计学数据证明了牙周炎与心血管病之间存在高度关联性,但其联系机制尚存在争议。近年来随着对牙周疾病和心血管疾病研究的不断深入,国内外学者将两者内在联系机制主要锁定在牙周致病菌的作用、长期慢性炎症影响、机体免疫反应以及内皮损伤上。本文对牙周炎及心血管疾病的关联性及其内在联系机制进行综述,旨在为牙周炎患者预防心血管疾病提供依据。As a chronic progressive inflammatory disease,periodontitis affects the health of the system to a certain extent.A large amount of statistical data proves that there is a high correlation between periodontitis and cardiovascular disease,but the connection mechanism is still controversial.In recent years,with the continuous in-depth research on periodontal disease and cardiovascular disease,domestic and foreign scholars have focused on the role of periodontal pathogens,long-term chronic inflammation,immune response,and endothelial damage.This article reviews the relationship between periodontitis and cardiovascular disease and its internal linkage mechanism,aiming to provide evidence for the prevention of cardiovascular disease in patients with periodontitis.

关 键 词：牙周炎 心血管疾病 牙周致病微生物 

分 类 号：R54[医药卫生—心血管疾病]