支气管扩张患者细胞免疫状态的评估分析  

The Analysis of Bronchiectasis Patients’ Cellular Immune State

作　　者：杨东霞[1] 武莉莉[1] 苏炜欣 肖稳娣 YANG Dong-xia;WU Li-li;SU Wei-xin;XIAO Wen-di(Shenzhen Second People's Hospital,the First Affiliated Hospital of Shenzhen University,Guangdong Shenzhen 518035)

机构地区：[1]深圳市第二人民医院深圳大学第一附属医院,广东深圳518035

出　　处：《深圳中西医结合杂志》2021年第4期8-10,共3页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

基　　金：深圳市科技计划项目资助课题(JCYJ20160425104021619)。

摘　　要：目的:评估支气管扩张患者的细胞免疫状态。方法:纳入深圳市第二人民医院2018年1月至2019年2月收治的33例支气管扩张患者为支气管扩张组,选取同期42例单纯肺部感染患者为肺炎组,选取同期37例健康体检者为健康组,检测其细胞免疫功能,观察血清CD3、CD4、CD8含量及血清维生素D水平并进行比较分析。结果:肺炎组CD3、CD4、CD8、维生素D水平均低于健康组,但差异无统计学意义(P>0.05);支气管扩张组CD3、CD4、CD8、维生素D水平均低于健康组和肺炎组,差异均具有统计学意义(P<0.05)。结论:支气管扩张患者存在细胞免疫功能紊乱。Objective To evaluate bronchiectasis patients’ cellular immune state.Methods 33 patients with bronchiectasis admitted to Shenzhen Second People’s Hospital from January 2018 to February 2019 were selected as bronchiectasis group,42 patients with simple pulmonary infection were selected as pneumonia group,and 37 healthy people were selected as healthy group.Detect their cellular immune function,investigate their serum CD3、CD4、CD8 and vitamin D level,comparative analysis of their difference.Results The pneumonia patient group’s serum CD3、CD4、CD8 and vitamin D level were lower than healthy people group’s,the difference was not statistically significant (P > 0.05).The bronchiectasis group’s serum CD3、CD4、CD8 and vitamin D level were significantly lower than pneumonia group’s and healthy group’s,the differences were statistically significant (P < 0.05).Conclusion Bronchiectasis patients’ cellular immune were disorders.

关 键 词：支气管扩张 肺炎 细胞免疫 

分 类 号：R562.2+2[医药卫生—呼吸系统] R446.1[医药卫生—内科学]