单手性半导体碳纳米管在生物成像中的研究进展  

Recent Progress of Biological Imaging Based on Monochiral Semiconducting Single-walled Carbon Nanotubes

作　　者：许文静 侯军才[1] 赵建文[2] XU Wenjing;HOU Juncai;ZHAO Jianwen(School of Materials Science and Engineering,Shaanxi University of Technology,Hanzhong 723000,Shaanxi,P.R.China;Printable Electronics Research Centre,Suzhou Institute of Nano-Tech and Nano-Bionics,Chinese Academy of Sciences,Suzhou 215123,Jiangsu,P.R.China)

机构地区：[1]陕西理工大学材料科学与工程学院,陕西汉中723000 [2]中国科学院苏州纳米技术与纳米仿生研究所印刷电子研究中心,江苏苏州215123

出　　处：《影像科学与光化学》2021年第3期348-353,共6页Imaging Science and Photochemistry

基　　金：国家重点研发计划(2020YFA0714700);国家自然基金面上项目(61874132);陕西省自然基金面上项目(2017JM5063)。

摘　　要：半导体碳纳米管在生物成像、光热疗法和运载药物等生物医学应用中都展现出明显的优势。特别是生物成像,半导体碳纳米管在近红外生物窗口(0.7~1.4μm)中显示出固有的荧光和强大的光学吸收。半导体碳纳米管不仅可以在体内深层成像中对细胞进行荧光标记,还可以追踪和治疗肿瘤细胞。半导体碳纳米管的电子能带结构和光、电性能均取决于它们的手性,应用于生物医学时,只有采用单手性半导体碳纳米管才能最大限度展现出碳纳米管本身的优势。单手性半导体碳纳米管的分离及其在新型光电子器件和生物荧光成像等相关应用一直是当今科技前沿中的研究热点。本论文将介绍半导体碳纳米管的分离技术和单手性碳纳米管在生物成像领域的研究进展。Semiconducting single-walled carbon nanotubes(sc-SWCNTs)have shown obvious advantages in biomedical applications such as biological imaging,photothermal therapy and drug delivery.In particular,they exhibit excellent properties for biological imaging due to their inherent fluorescence and strong optical absorption in the near infrared biological window(0.7-1.4μm).Sc-SWCNT can be used in not only fluorescently labeling cells in deep imaging in vivo,but also tracking and treating tumor cells,which have attracted widespread attention.The electronic band structure and photoelectric properties of sc-SWCNTs depend on their chirality.The advantages of sc-SWCNTs themselves can be maximized only when using monochiral sc-SWCNTs for biomedical applications.The separation of monochiral sc-SWCNTs and their applications in new optoelectronic devices and bioluminescence imaging have become research hotspots at the forefront of science and technology.In this paper,we will introduce the separation technology of sc-SWCNTs and the research progress of monochiral sc-SWCNTs in the field of biological imaging.

关 键 词：半导体碳纳米管 单手性 分离技术 生物成像 

分 类 号：R318[医药卫生—生物医学工程] TB383.1[医药卫生—基础医学]