Phylogenetic patterns suggest frequent multiple origins of secondary metabolites across the seed-plant‘tree of life’  

作　　者：Yongzeng Zhang Tao Deng Lu Sun Jacob B.Landis Michael J.Moore Hengchang Wang Yuehua Wang Xiaojiang Hao Jijun Chen Shenghong Li Maonian Xu Pema-Tenzin Puno Peter H.Raven Hang Sun 

机构地区：[1]CAS Key Laboratory for Plant Diversity and Biogeography of EastAsia,Kunming Instituteof Botany,Chinese Academy of Sciences,Kunming 650201,China [2]University of the Chinese Academy of Sciences,Beijing 100049,China [3]Department of Botany and Plant Sciences,University of California Riverside,Riverside,CA92521,USA [4]School of Integrative Plant Science,Section of Plant Biology and the L.H.Bailey Hortorium,Cornell University,Ithaca,NY 14853,USA [5]Department of Biology,Oberlin College,Oberlin,OH 44074,USA [6]CAS Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture,Chinese Academy of Sciences,Wuhan 430074,China [7]Schoolof Life Science,Yunnan University,Kunming 650091,China [8]State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201,China [9]Pharmaceutical Sciences,University of Iceland,107 Reykjavik,Icel and [10]Missouri Botanical Garden,St.Louis,MO 63110,USA

出　　处：《National Science Review》2021年第4期61-72,共12页国家科学评论（英文版）

基　　金：supported by the Major Program of the National Natural Science Foundation of China(31590823 to H.S.);the National Key R&D Program of China(2017YFC0505200 to H.S.);the Strategic Priority Research Program of Chinese Academy of Sciences(XDA 20050203 to H.S.)。

摘　　要：To evaluate the phylogenetic patterns of the distribution and evolution of plant secondary metabolites(PSMs),we selected 8 classes of PSMs and mapped them onto an updated phylogenetic tree including 437 families of seed plants.A significant phylogenetic signal was detected in 17 of the 18 tested seed-plant clades for at least 1 of the 8 PSM classes using the D statistic.The phylogenetic signal,nevertheless,indicated weak clustering of PSMs compared to a random distribution across all seed plants.The observed signal suggests strong diversifying selection during seed-plant evolution and/or relatively weak evolutionary constraints on the evolution of PSMs.In the survey of the current phylogenetic distributions of PSMs,we found that multiple origins of PSM biosynthesis due to external selective forces for diverse genetic pathways may have played important roles.In contrast,a single origin of PSMs seems rather uncommon.The distribution patterns for PSMs observed in this study may also be useful in the search for natural compounds for medicinal purposes.

关 键 词：secondary metabolites phylogenetic tree phylogenetic signal co-diversification evolution BIOPROSPECTING seed plants 

分 类 号：Q943.2[生物学—植物学]