One-pot two-step reaction of selenosulfonate with isocyanides and allyl alcohol under aqueous conditions:Atom-economic synthesis of selenocarbamates and allyl sulfones  

作　　者：Jing-Jing Ai Jian Li Shun-Jun Ji Shun-Yi Wang 

机构地区：[1]Key Laboratory of Organic Synthesis of Jiangsu Province,College of Chemistry,Chemical Engineering and Materials Science&Collaborative Innovation Center of Suzhou Nano Science and Technology,Soochow University,Suzhou 215123,China

出　　处：《Chinese Chemical Letters》2021年第2期721-724,共4页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China (Nos.21971174,21772137,21672157);the Ph.D.Programs Foundation of PAPD;the Project of Scientific and Technologic Infrastructure of Suzhou (No.SZS201708);the Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions (No. 16KJA150002);Soochow University,and State and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials for financial support。

摘　　要：In many reactions involving selenosulfonate or thiosulfonate,the sutfone group often leaves in form of benzenesutfinic acid or sodium benzenesulfinate.A one-pot two-step reaction of selenosulfonate with isocyanides and allyl alcohol under aqueous conditions to afford selenocarbamates and allyl sulfone compounds is reported.The sulfinic acid as the first-step side product is converted to the allyl sulfone compound by water promoted reaction with allyl alcohol.Water acts as both an oxygen source of selenocarbamates and as a promoter to drive the second step reactio n.The reactions have the advantages of mild conditions,green,environment-friendly,and high atomic economy.

关 键 词：Aqueous conditions One-pot two-step process Benzenesulfinic acid Selenocarbamate Allyl sulfone compound 

分 类 号：O623.83[理学—有机化学] O623.624[理学—化学]