理气活血方联合孕三烯酮在卵巢型子宫内膜异位症腹腔镜保守性手术后的应用效果  

Application effect of Liqi Huoxue Decoction combined with Gestrienone in the treatment of ovarian endometriosis after laparoscopic conservative surgery

作　　者：郑颖惠 陈璇琼 ZHENG Ying-hui;CHEN Xuan-qiong(Department of Gynecology,Guangzhou Hospital of Integrated Traditional and Western Medicine,Guangdong Province,Guangzhou510800,China)

机构地区：[1]广州市中西医结合医院妇科,广东广州510800

出　　处：《中国当代医药》2021年第14期177-180,共4页China Modern Medicine

摘　　要：目的探讨理气活血方联合孕三烯酮在卵巢型子宫内膜异位症(OEMs)腹腔镜保守性手术后的临床效果。方法选取2017年6月~2019年6月在广州市中西医结合医院行OEMs腹腔镜保守性手术的68例患者作为研究对象,按照随机数字表法分为对照组与观察组,每组各34例。对照组术后口服孕三烯酮胶囊,观察组患者在对照组基础上加服理气活血方,两组治疗3个月。比较两组患者治疗前后痛经持续时间,视觉模拟量表(VAS)评分,血清雌二醇(E2)、卵泡刺激素(FSH)、癌抗原125(CA125)水平及抗子宫内膜抗体(EMAb)阳性率。结果治疗后两组的痛经持续时间短于治疗前,VAS评分、E2、FSH、CA125水平、EMAb阳性率均低于治疗前,差异有统计学意义(P<0.05),且观察组治疗后的痛经持续时间短于对照组,VAS评分、E2、FSH、CA125水平、EMAb阳性率均低于对照组,差异有统计学意义(P<0.05)。结论理气活血方联合孕三烯酮治疗OEMs腹腔镜保守性手术后患者,能够明显缩短痛经时间,降低VAS评分,降低血清E2、FSH、CA125水平和EMAb阳性率,具有较好的疗效。Objective To observe the clinical effect of Liqi Huoxue Decoction combined with Gestrinone on the treatment of ovarian endometriosis(OEMs)after laparoscopic conservative surgery.Methods A total of 68 patients with OEMs undergoing laparoscopic conservative surgery who treated in Guangzhou Hospital of Integrated Traditional and Western Medicine from June 2017 to June 2019 were selected as the research objects.According to random number table method,they were divided into control group and observation group,34 cases in each group.The control group was orally taken Gestrinone Capsule after surgery,and the observation group was additively taken Liqi Huoxue Decoction on the basis of the control group.The two groups were treated for 3 months.The duration of dysmenorrhea,visual analog scale(VAS)score,serum estradiol(E2),follicle stimulating hormone(FSH),cancer antigen 125(CA125)and positive rate of anti-endometrial antibody(EMAb)were compared between two groups before and after treatment.Results After treatment,the duration of dysmenorrhea in both groups was shorter than before treatment,VAS score,levels of E2,FSH,CA125 and positive rate of EMAb were lower than before treatment,the differences were statistically significant(P<0.05).The duration of dysmenorrhea after treatment in the observation group was shorter than that in the control group,the VAS score,E2,FSH,CA125 levels and the positive rate of EMAb were all lower in the observation group than those in the control group,the differences were statistically significant(P<0.05).Conclusion Liqi Huoxue Decoction combined with Gestrinone in the treatment of patients with OEMs after laparoscopic conservative surgery can significantly shorten the dysmenorrhea time,reduce the VAS score,reduce the serum E2,FSH,CA125 levels and EMAb positive rate,and has a good curative effect.

关 键 词：卵巢型子宫内膜异位症 理气活血方 孕三烯酮 性激素 癌抗原125 抗子宫内膜抗体 

分 类 号：R711.71[医药卫生—妇产科学]