动脉血流参数对孕早期先兆流产的预测价值及预后的关系  

Relationship between Arterial Blood Flow Parameters and Prognosis of Threatened Abortion in Early Pregnancy

作　　者：张礼英[1] 丁媛媛[1] 孙雅琴[1] ZHANG Liying;DING Yuanyuan;SUN Yaqin(Ordos Central Hospital, Inner Mongolia Ordos 017000, China)

机构地区：[1]内蒙古鄂尔多斯市中心医院,内蒙古鄂尔多斯017000

出　　处：《河北医学》2021年第5期827-830,共4页Hebei Medicine

基　　金：鄂尔多斯市应用技术研究与开发资金计划,(编号:鄂财教指[2018]516号)。

摘　　要：目的:探讨动脉血流参数对孕早期先兆流产的预测价值及预后的关系。方法:选取2017年1月至2018年1月在我院就诊的孕期5~8周先兆流孕妇女200例作为研究组,并选择正常早期宫内妊娠妇女100例作为对照组,所有患者均行经腹部超声,子宫动脉血流参数进行测量,所有孕妇均随访至16周,研究组孕妇中保胎失败者作为保胎失败组(102例),保胎成功者作为保胎成功组(98例),比较三组患者动脉血流参数,并对动脉血流参数对于妊娠结局诊断价值进行比较,比较三组孕妇血清孕酮和β-HCG水平,并对研究组和对照组子宫内膜厚度和子宫内膜血管化参数进行比较。结果:三组孕妇收缩期峰值流速无明显差异(P>0.05);保胎失败组孕妇舒张末期流速低于保胎成功组和对照组,搏动指数、阻力指数高于保胎成功组和对照组(P<0.05);保胎成功组舒张末期流速、搏动指数、阻力指数高于对照组孕妇(P<0.05)。子宫动脉血流参数截断值、敏感性、特异性均具有良好诊断价值。受试者工作曲线表明,收缩期峰值流速/舒张末期流速(S/D)、搏动指数(PI)、阻力指数(RI)都具有较好的诊断价值。保胎成功组、保胎失败组血清孕酮、β-HCG水平均低于对照组,且保胎失败组血清孕酮和β-HCG水平低于保胎成功组(P<0.05)。两组孕妇子宫内膜厚度差异无统计学意义(P>0.05);研究组子宫内膜容积、血管指数(VI)、血流指数(FI)、血管血流指数(VFI)均低于对照组(P<0.05)。结论:动脉血流参数对孕早期先兆流产具有较高的预测价值,其敏感度和特异度均较高,有益于孕妇预后,值得临床进一步推广。Objective:To investigate the predictive value of arterial blood flow parameters on threatened abortion in early pregnancy and its relationship with prognosis.Methods:200 pregnant women with threatened abortion of 5-8 weeks in our hospital from January 2017 to January 2018 were selected as the study group,and 100 normal early intrauterine pregnancy women were selected as the control group.All patients underwent transabdominal ultrasound,uterine artery blood flow parameters were measured,and all pregnant women were followed up to 16 weeks.In the study group,102 cases of pregnant women with failure of fetal protection were regarded as failure group,98 cases of pregnant women with success of fetal protection were regarded as success group.The arterial blood flow parameters of the three groups were compared,and the diagnostic value of the arterial blood flow parameters for pregnancy outcome was compared.The serum progesterone andβ-hcg levels of the three groups were compared,and the endometrial thickness and the endometrial vascularization parameters of the study group and the control group were compared.Results:There was no significant difference in the peak systolic flow rate of the three groups of pregnant women(P>0.05);the end-diastolic flow rate of the pregnant women in the failed pregnancy loss group was lower than that in the successful pregnancy loss group and the control group,and the pulsation index and resistance index were higher than those in the successful pregnancy loss group and the control group(P<0.05);the end-diastolic flow rate,pulsatility index,and resistance index of the successful fetal pregnancy group were higher than those of the control group(P<0.05).The cut-off value,sensitivity and specificity of uterine artery blood flow parameters have good diagnostic value.The receiver operating curve shows that the peak systolic flow rate/end-diastolic flow rate(S/D),pulsatility index(PI),and resistance index(RI)all have good diagnostic value.The levels of serum progesterone andβ-HCG in the successful

关 键 词：动脉血流参数 孕早期先兆流产 预测价值 预后 

分 类 号：R71[医药卫生—妇产科学]