westgard西格玛规则在同型半胱氨酸室内质控中的应用  

Application of Westgard Sigma Rule in Homocysteine Indoor Quality Control

作　　者：卢莎莎 段勇波 郝香莉 LU Sha-sha;DUAN Yong-bo;HAO Xiang-li(Department of Laboratory Medicine,ShangLuu Center for Disease Control and Prevention,Shangluo 726000)

机构地区：[1]陕西省商洛市疾病预防控制中心检验科,陕西商洛726000 [2]陕西省澄城县中医医院检验科,陕西澄城715200

出　　处：《医学临床研究》2021年第4期512-514,共3页Journal of Clinical Research

基　　金：陕西省重点研发计划项目(2017SF-264)。

摘　　要：[目的]探讨westgard西格玛规则在同型半胱氨酸(HCY)室内质量控制中的应用与评价。[方法]选取2018年1~6月(westgard西格玛规则使用前)和2018年7~12月(westgard西格玛规则使用后)HCY检测的质控值.分析两种质控方法的失控率、不精密度(CV)、偏倚(Bias)和σ值。[结果]westgard西格玛规则使用前HCY检测的总失控率为2.21%,使用后HCY检测总失控率为1.27%。westgard西格玛规则使用HCY室内质量评价的平均Bias和CV分别为2.50%和7.17%,使用后的平均Bias和CV分别为1.82%和5.66%。westgard西格玛规则使用前低、中、高不同浓度HCY室内质量评价的σ值为7.32.7.89和8.17.均大于6;使用后低、中、高不同浓度HCY室内质量评价的σ值为5.53.5.85和6.04.即westgard西格玛规则使用后的σ值低于使用前。[结论]westgard西格玛规则可用于HCY的室内质量检测和指导质量改进,具有临床应用价值。[Objective]To explore the application and evaluation of Westgard sigma rule in the quality con-trol of homocysteine(HCY).[Methods]The quality control values of HCY detection from January 2018 to June 2018(before the use of the w estgard Sigma rule)and July 2018 to December 2018(after the use of the Westgard Sigma rule)were selected to analyze the out of-control rate,CV,Bias and theσvalues of the two quality control methods.[Results]The total out-of control rate of HCY detection was 2.21%before using Westgard Sigma rule and 1.27%after using HCY rule.The average Bias and CV of Westgard Sigma rule using HCY indoor quality asssment were 2.50%and 7.17%,respectively,and the average Bias and CV after using HCY were 1.82%and 5.66%,respectively.The o values of low,medium and high HCY indoor quality evalua-tion before using the Westgard Sigma rule were 7.32.7.89 and 8.17.which were all greater than 6.Theσval-ues of low,medium and high HCY indoor quality evaluation after using were 5.53.5.85 and 6.04.that is,theσvalues after using the Westgard Sigma rule were lower than before using.[Conclusion]Westgard Sigma rule can be used for HCY indoor quality testing and quality improverment,and has clinical application value.

关 键 词：半胱氨酸 逻辑学 质量控制 

分 类 号：R954.2[医药卫生—药学]