慢性心力衰竭的药物治疗进展  

Progress in drug therapy for chronic heart failure

作　　者：何海潇 HE Hai-xiao(Department of Cardiology,Tianjin Jizhou District Bangjun Town Central Health Center,Tianjin 301901,China)

机构地区：[1]天津市蓟州区邦均镇中心卫生院心内科,天津301901

出　　处：《中国城乡企业卫生》2021年第4期43-45,共3页Chinese Journal of Urban and Rural Enterprise Hygiene

摘　　要：心力衰竭指心脏结构、功能异常引起心室充盈、射血能力受损的临床综合征,为多种心脏疾病的终末期表现,已成为危害人类健康的主要疾患之一。现阶段,临床治疗慢性心力衰竭仍以药物治疗为主,随着临床研究的深入,慢性心力衰竭患者可选择的药物越来越多,疗效也不尽相同。慢性心力衰竭临床治疗中,经典抗心力衰竭方案也存在一些不足,而新型抗心力衰竭药物为经典治疗方案的更新和补充。本文综述了神经内分泌调节药物(血管紧张素转换酶抑制剂、β受体阻滞剂、血管紧张素Ⅱ受体拮抗剂、醛固酮受体拮抗剂)、强心药、利尿剂及新型药对慢性心力衰竭的疗效及存在的问题,以期为临床治疗慢性心力衰竭提供参考依据。Heart failure refers to the clinical syndrome of ventricular filling and ejection dysfunction caused by abnormal cardiac structure and function. It is the end-stage manifestation of a variety of heart diseases and has become one of the main diseases endangering human health. At this stage,the clinical treatment of chronic heart failure is still dominated by drug therapy. With the deepening of clinical research,patients with chronic heart failure can choose more and more drugs,and the curative effect is not the same. In the clinical treatment of chronic heart failure,there are some deficiencies in the classic anti heart failure scheme,while new anti heart failure drugs are the update and supplement of the classic treatment scheme.This article reviews the effects and problems of neuroendocrine drugs(angiotensin converting enzyme inhibitors, beta blockers, angiotensin Ⅱ receptor antagonists, aldosterone receptor antagonists),cardiotonics,diuretics and new drugs on chronic heart failure,in order to provide reference for clinical treatment of chronic heart failure.

关 键 词：慢性心力衰竭 神经内分泌调节药物 强心药 利尿剂 

分 类 号：R541.6[医药卫生—心血管疾病]