自然流产患者的甲状腺功能状态、妊娠次数、人工流产次数对体内激素水平的影响  

Survey on the Thyroid Function State and Effects of Pregnancy and Induced Abortion Number on the Hormone Contents for Spontaneous Abortion Patients

作　　者：潘婷华 PAN Tinghua(Department of Obstetrics,Guangdong Provincial Integrated Chinese and Western Medicine Hospital,Guangzhou 510000,China)

机构地区：[1]广东省中西医结合医院产科,广东广州510000

出　　处：《中国医药指南》2021年第10期40-42,共3页Guide of China Medicine

摘　　要：目的探讨自然流产患者的甲状腺功能状态、妊娠次数、人工流产次数对体内激素水平的影响。方法选取我院2018年4月至2019年5月收治的62例自然流产患者作为研究组,选择同期我院有过正常生育且无不良孕产史的62例同龄女性作为对照组,观察两组入选者妊娠次数、人工流产次数与体内激素水平的相关性。结果两组入选者的游离三碘甲状腺原氨酸(free triiodothyronine,FT3)比较,差异无统计学意义(P>0.05);研究组甲状腺正常女性与异常患者的子宫异常、妇科内分泌与TORCH异常比例比较,差异无统计学意义(P>0.05);研究组促甲状腺激素(thyroid stimulating hormone,TSH)、抗甲状腺过氧化物酶自身抗体(anti thyroid peroxidase autoantibody,TPOAb)高于对照组,FT4低于对照组(P<0.05);研究组甲状腺功能正常比例低于对照组,总异常率高于对照组,差异有统计学意义(P<0.05)。自然流产与年龄、人工流产次数、激素之间无相关性,与妊娠次数、生产次数之间呈正相关(P<0.05)。结论自然流产的发生与妊娠次数、生产次数之间存在一定联系,对于这类患者需及时警惕其甲状腺水平,降低自然流产的概率。Objective To study the thyroid function state and effects of pregnancy and induced abortion number on the hormone contents for spontaneous abortion patients.Methods Sixty-two patients with spontaneous abortion admitted in our hospital from April 2018 to May 2019 were selected as the study group,and 62 women of the same age who had normal births and no history of adverse pregnancy and childbirth in our hospital during the same period were selected as the control group.The correlation of pregnancy and induced abortion number with hormone contents was analyzed.Results There was no statistically significant difference in free triiodothyronine(FT3)between the two groups of candidates(P>0.05);there was no significant difference in uterine abnormalities,gynecological endocrine and TORCH abnormalities between patients with normal thyroid and abnormal thyroid patients in the study group(P>0.05).The Thyroid stimulating hormone(TSH)and anti thyroid peroxidase autoantibody(TPOAb)of the study group were higher than those of the control group,and FT4 was lower than that of the control group(P<0.05);the proportion of normal thyroid function in the study group was lower than that of the control group,and the total abnormal rate was higher than that of the control group,the difference was statistically significant(P<0.05).There was no correlation between spontaneous abortion and age,number of induced abortions and hormones,but positive correlation between number of pregnancy and number of births(P<0.05).Conclusion The occurrences of spontaneous abortion are related with the number of pregnancy and delivery.In order to reduce the spontaneous abortion rate,such kind of patients shall be focused to monitor their thyroid function.

关 键 词：自然流产 甲状腺功能 妊娠次数 人工流产 激素 

分 类 号：R714.21[医药卫生—妇产科学]