新生儿呼吸窘迫早期无创呼吸支持应用效果评价  

Evaluation of noninvasive respiratory support application in early stage of neonatal respiratory distress

作　　者：李俊标 何慧民 曹建宁 陈飞 何水真 侯文婷 Li Junbiao;He Huimin;Cao Jianning(The Dongxiang District People's Hospital of Fuzhou City,Fuzhou,Jiangxi,331800;The People's Hospital of Nancheng County,Nancheng,Jiangxi 331800)

机构地区：[1]抚州市东乡区人民医院,江西抚州331800 [2]南城县人民医院,江西南城331800

出　　处：《基层医学论坛》2021年第14期1936-1938,共3页The Medical Forum

基　　金：抚州市社会发展指导性科技计划项目(抚科计字-149)。

摘　　要：目的评价新生儿呼吸窘迫早期无创呼吸支持的应用效果。方法选择2019年1月—2020年8月抚州市东乡区人民医院收治的84例新生儿呼吸窘迫综合征(NRDS)患儿,按随机数字表法将其分为2组各42例。入选患儿均接受吸痰、叩背及抗感染等治疗,对照组采用鼻导管给氧,观察组采用经鼻持续气道正压通气(CAPA)治疗。比较2组临床症状改善时间及血气指标[血氧饱和度(SpO2)、pH、动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)]。结果观察组吸气性三凹征、气促及进行性呼吸困难改善时间短于对照组,治疗后SpO2、高于对照组,PaCO2低于对照组,均有统计学差异(P<0.05)。结论CPAP治疗NRDS能够快速控制患儿病情,有利于消除临床症状,且能够促使血气指标得以改善,值得临床推广。Objective To evaluate the effect of non-invasive respiratory support in the early stage of neonatal respiratory distress.Methods Eighty-four cases of neonatal respiratory distress syndrome(NRDS)treated in our hospital from January 2019 to August 2020 were selected and divided into two groups according to random number table method,with 42 cases in both groups.All the enrolled children received sputum aspiration,back pat and anti-infection treatment.The control group was given oxygen through nasal catheter,and the observation group was treated with nasal continuous positive airway pressure(CAPA).The improvement time of clinical symptoms and blood gas indexes(SpO2,pH,PaO2,PaCO2)were compared between the two groups.Results The improvement time of the observation group was shorter than that of the control group.After treatment,SpO2,pH and PaO2 were higher than those of the control group,and PaCO2 was lower than those of the control group,with statistical differences(P<0.05).Conclusion CPAP treatment of NRDS can quickly control the condition of children,is beneficial to eliminate the clinical symptoms of children,and can promote the improvement of blood gas indexes,can be used as an effective method for the treatment of NRDS in clinical promotion.

关 键 词：新生儿呼吸窘迫 早期 经鼻持续气道正压通气 鼻导管给氧 血气指标 

分 类 号：R4[医药卫生—临床医学]