加温湿化高流量鼻导管通气辅助药物治疗新生儿肺炎的临床效果  

Clinical effect of warming humidifying high flow nasal catheter ventilation assisted drug in the treatment of neonatal pneumonia

作　　者：赵合芬 ZHAO Hefen(Neonatology Department,the People's Hospital of Yucheng County,Shangqiu 476300,China)

机构地区：[1]虞城县人民医院新生儿科,河南商丘476300

出　　处：《临床医学研究与实践》2021年第15期78-80,共3页Clinical Research and Practice

摘　　要：目的探讨加温湿化高流量鼻导管通气辅助药物治疗新生儿肺炎的临床效果。方法选择我院2018年8月至2019年12月收治的90例新生儿肺炎患儿,以抽签法将其分为对照组与观察组,每组45例。对照组给予阿莫西林克拉维酸钾药物治疗,观察组在对照组基础上联合加温湿化高流量鼻导管通气治疗。比较两组的临床疗效、血气指标、临床指标及并发症发生情况。结果观察组的治疗总有效率高于对照组,差异具有统计学意义(P<0.05)。治疗后,两组的PaO_(2)、SaO_(2)均较治疗前升高,PaCO_(2)均较治疗前降低,且观察组优于对照组(P<0.05)。观察组的呼吸困难消失时间、心率恢复正常时间、住院时间均短于对照组(P<0.05)。观察组的并发症总发生率低于对照组,差异具有统计学意义(P<0.05)。结论加温湿化高流量鼻导管通气辅助药物治疗新生儿肺炎的临床效果显著,可显著改善患儿的血气指标,缓解临床症状,降低并发症发生率,值得临床应用和推广。Objective To investigate the clinical effect of warming humidifying high flow nasal catheter ventilation assisted drug in the treatment of neonatal pneumonia.Methods Ninety children with neonatal pneumonia treated in our hospital from August 2018 to December 2019 were selected and divided into control group and observation group by drawing lots,with 45 cases in each group.The control group was treated with amoxicillin and clavulanate potassium,and the observation group was treated with warming humidifying high flow nasal catheter ventilation on the basis of the control group.The clinical efficacy,blood gas indexes,clinical indexes and complications of the two groups were compared.Results The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).After treatment,PaO_(2) and SaO_(2) of the two groups were higher than those before treatment,PaCO_(2) was lower than that before treatment,and those of the observation group were better than the control group(P<0.05).The time of dyspnea disappearance,time of heart rate recovery and hospital stay time in the observation group were shorter than those in the control group(P<0.05).The total incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Warming humidifying high flow nasal catheter ventilation assisted drug in the treatment of neonatal pneumonia has significant clinical effect,it can significantly improve the blood gas indexes,relieve the clinical symptoms and reduce the incidence of complications,which is worthy of clinical application and promotion.

关 键 词：加温湿化高流量鼻导管通气 阿莫西林克拉维酸钾 新生儿肺炎 血气指标 

分 类 号：R722.135[医药卫生—儿科]